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17764 Mtf1

17764

Mtf1

metal response element binding transcription factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition metal response element binding transcription factor 1

研究结论

Date Results Publications
2016-10-01 10:54:00 Findings identify a reciprocal activation mechanism involving HIF-2alpha and the zinc-ZIP8-MTF1 axis during osteoarthritis pathogenesis that amplifies catabolic signaling and cartilage destruction. 26241779
2016-05-14 10:09:00 MTF1 mediates the increase of CaV3.2 mRNA and a rise in intracellular Zn(2+) which is associated with status epilepticus. 26498180
2013-09-21 12:33:00 the presence of SUMO moiety allows the MTF-1 protein to interact directly with metal-responsive element 23347955
2012-08-18 10:18:00 nuclear receptor SHP inhibits zinc-dependent induction of Dnmt1 by antagonizing metal-responsive transcription factor-1. 22362755
2012-03-10 11:43:00 MTF-1 DNA-binding activity is strongly enhanced in the presence of zinc. 22087877

名称对应

Type IDs
Synonymous MTF-1, Thyls
Gene
UniProtKB-ID: MTF1_MOUSE, Q8BSY2_MOUSE
UniprotKB: Q07243, Q8BSY2
UniParc: UPI00000E74F2, UPI00000EAC30
EMBL: BC017679, AK030284, AJ251880, X71327, AL606933, CH466552
Ensembl: ENSMUSG00000028890
KO: mmu:17764
Nucleutide sequences
EMBL-CDS: CAB71344.1, CAA50470.1, AAH17679.1, EDL30350.1, BAC26879.1
Ensembl_TRS: ENSMUST00000106193, ENSMUST00000030723
Protein sequencees
Ensembl_PRO: ENSMUSP00000101799, ENSMUSP00000030723
RefSeq: NP_032662.3
Others
UniRef100: UniRef100_Q8BSY2, UniRef100_Q07243
UniRef90: UniRef90_Q07243
UniRef50: UniRef50_Q07243
UniGene: Mm.272397
CCDS: CCDS18627.1

全选

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研究热度

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