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177602 sax-7

177602

sax-7

Sensory AXon guidance

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Sensory AXon guidance

研究结论

Date Results Publications
2021-01-02 12:53:00 Harmonization of L1CAM expression facilitates axon outgrowth and guidance of a motor neuron. 32994172
2020-08-15 14:43:00 dendrite development in C elegans requires the adhesion protein SAX-7/L1CAM and the cytoplasmic protein GRDN-1/CCDC88C to anchor dendrite endings at the nose 31988188
2019-01-26 12:22:00 loss of the cell adhesion molecule (CAM) CDH-4/Fat-like cadherin causes dendrites to be ordered randomly, despite remaining bundled. Loss of the CAMs PTP-3/LAR or SAX-7/L1CAM causes dendrites to adopt an altered order, which becomes increasingly random as animals grow. 30117807
2018-08-04 10:47:00 EFF-1 control dendrite morphology by regulating the localization pattern of SAX-7 in epidermal cells 29074578
2013-12-21 11:26:00 The ligand complex SAX-7/L1CAM and MNR-1 function at defined locations in the surrounding hypodermal tissue, whereas DMA-1 acts as the cognate receptor on the sensory neuron PVD. Mutations in this complex lead to dramatic defects in the formation, stabilization, and organization of the dendritic arbor. 24120131

名称对应

Type IDs
Gene
UniProtKB-ID: Q53U87_CAEEL, Q53U86_CAEEL, Q4PIU9_CAEEL, Q18100_CAEEL, W6RTH3_CAEEL, W6RRX6_CAEEL
UniprotKB: Q53U87, Q53U86, Q4PIU9, Q18100, W6RTH3, W6RRX6
UniParc: UPI000050A481, UPI0003E9DB42, UPI000053F5E4, UPI000050A480, UPI000042700F, UPI0003E9D316
EMBL: AB206669, AB206670, BX284604
EnsemblGenome: WBGene00004732
KO: cel:CELE_C18F3.2
Nucleutide sequences
EMBL-CDS: BAD97388.1, CCD65186.1, BAD97389.1, CCD65187.1, CCD65185.1, CCD65184.1, CDM63517.1, CDM63516.1
Gene_ORFName: CELE_C18F3.2, C18F3.2, CELE_C18F3.2, C18F3.2, C18F3.2, CELE_C18F3.2, C18F3.2, CELE_C18F3.2, C18F3.2, CELE_C18F3.2, CELE_C18F3.2, C18F3.2
Protein sequencees
RefSeq: NP_001033397.1, NP_001033394.1, NP_001294162.1, NP_001294161.1, NP_001033395.1, NP_001033396.1
Others
UniRef100: UniRef100_Q18100, UniRef100_Q53U87, UniRef100_Q4PIU9, UniRef100_W6RTH3, UniRef100_W6RRX6, UniRef100_Q53U86
UniRef90: UniRef90_Q18100, UniRef90_Q53U87, UniRef90_W6RRX6
UniRef50: UniRef50_Q18100, UniRef50_Q53U87, UniRef50_W6RRX6
UniGene: Cel.17136

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