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17760 Map6

17760

Map6

microtubule-associated protein 6

protein-coding

Mus musculus

基因描述

Type Description
Definition microtubule-associated protein 6

研究结论

Date Results Publications
2020-07-25 11:20:00 This is the first study to describe MAP6 as a glycoprotein containing Gal-(beta-1,3)-GalNAc oligosaccharides and to show that hyperglycosylation of MAP6 is strongly associated with the pathogenesis of Parkinson's Disease. 31289257
2018-12-22 11:55:00 MAP6 deletion results in alterations of microtubule network, sarcoplasmic reticulum organization and calcium release. 30231928
2018-12-22 11:55:00 MAP6 is involved in the formation and the maintenance of mature post-synaptic dendritic spines.MAP6 is involved in the stabilisation of actin filaments in dendritic spines. 30224655
2018-07-28 11:49:00 show that MAP6 proteins interact directly with both Tctex1 and the C-terminus of Cav2.2/N-type calcium channels. 29094416
2017-07-29 11:09:00 MAP6 is present at the Golgi complex and in secretory vesicles in unpolarized cells and re-distributed to newly forming axons, where it binds and stabilizes axonal microtubules. A palmitoylation cycle controls MAP6 membrane-microtubule shuttling and is required for its polarized distribution in axons. 28521134

名称对应

Type IDs
Synonymous 2810411E12Rik, Map-6, Mtap6, STOP
Gene
UniProtKB-ID: MAP6_MOUSE
UniprotKB: Q7TSJ2
UniParc: UPI00001A3D18, UPI0000563FA3, UPI0000E0DB2F
EMBL: Y16008, Y14754, BC053039, Y14756, Y16032, Y14755
Ensembl: ENSMUSG00000055407
KO: mmu:17760
Nucleutide sequences
EMBL-CDS: CAA75930.1, AAH53039.1, CAA75989.1, CAA75049.1
Ensembl_TRS: ENSMUST00000208605, ENSMUST00000068973, ENSMUST00000127492, ENSMUST00000107100, ENSMUST00000207883
Protein sequencees
Ensembl_PRO: ENSMUSP00000146585, ENSMUSP00000102717, ENSMUSP00000146340, ENSMUSP00000064787, ENSMUSP00000146897
RefSeq: NP_034967.2, NP_001041632.1, NP_001036820.2
Others
UniRef100: UniRef100_Q7TSJ2
UniRef90: UniRef90_Q63560
UniRef50: UniRef50_Q63560
UniGene: Mm.154087
CCDS: CCDS40029.1, CCDS21479.1, CCDS85345.1

全选

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