nhr-8 - Nuclear hormone receptor family member nhr-8-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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177551 nhr-8

基因描述

Type	Description
Definition	Nuclear hormone receptor family member nhr-8

研究结论

Date	Results	Publications
2017-06-03 10:48:00	Pdda is abolished by synthetic ascarosides and steroidal ligands of the nuclear hormone receptor DAF-12. We show that neither ascarosides nor any known steroid hormones are required for Pdda and that another chemical signal mediates this phenotype, in part via the nuclear hormone receptor NHR-8.	28394895
2015-07-25 11:42:00	Dafachronic acid signaling through NHR-8 is essential for diet restriction-mediated longevity.	25209682
2015-07-25 10:40:00	Knockdown of the NHR-8 nuclear receptor enhanced sensitivity to the lipid-reducing activity of alkaloids in Caenorhabditis elegans.	25052035
2014-04-05 11:49:00	C. elegans NHR-8 NR, a homolog of vertebrate liver X and vitamin D receptors, regulates nematode cholesterol balance, fatty acid desaturation, apolipoprotein production, and bile acid metabolism.	23931753

名称对应

Type	IDs
Gene	UniProtKB-ID: NHR8_CAEEL UniprotKB: Q9XYB7 UniParc: UPI000013003F, UPI0000191DE3 EMBL: AF083226, FO080445 EnsemblGenome: WBGene00003607 KO: cel:CELE_F33D4.1
Nucleutide sequences	EMBL-CDS: CCD63762.1, AAD03684.1, CCD63761.1 Gene_ORFName: F33D4.1 EnsemblGenome_TRS: F33D4.1b.1, F33D4.1a.1
Protein sequencees	EnsemblGenome_PRO: F33D4.1a.1, F33D4.1b.1 RefSeq: NP_741445.1, NP_001023169.1
Others	UniRef100: UniRef100_Q9XYB7 UniRef90: UniRef90_Q9XYB7 UniRef50: UniRef50_Q9XYB7 UniGene: Cel.18186

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mRNA

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Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31308550	EPIC: software toolkit for elution profile-based inference of protein complexes. Nat Methods Lucas ZhongMing Hu , Florian Goebels , June H Tan , Eric Wolf , Uros Kuzmanov , Cuihong Wan , Sadhna Phanse , Changjiang Xu , Mike Schertzberg , Andrew G Fraser , Gary D Bader , Andrew Emili	2019-08-01	-
28394895	Larval crowding accelerates C. elegans development and reduces lifespan. PLoS Genet. Andreas H Ludewig , Clotilde Gimond , Joshua C Judkins , Staci Thornton , Dania C Pulido , Robert J Micikas , Frank DÃ¶ring , Adam Antebi , Christian Braendle , Frank C Schroeder	2017-04-01	-
25209682	Steroid hormone signalling links reproduction to lifespan in dietary-restricted Caenorhabditis elegans. Nat Commun Manjunatha Thondamal , Michael Witting , Philippe Schmitt-Kopplin , Hugo Aguilaniu	2014-01-01	let-363, nhr-8, daf-9
25052035	Knockdown of the NHR-8 nuclear receptor enhanced sensitivity to the lipid-reducing activity of alkaloids in Caenorhabditis elegans. Biosci. Biotechnol. Biochem. Yit-Lai Chow , Yuriko Kawasaki , Fumihiko Sato	2014-01-01	nhr-8
23931753	The NHR-8 nuclear receptor regulates cholesterol and bile acid homeostasis in C. elegans. Cell Metab. Daniel B Magner , Joshua Wollam , Yidong Shen , Caroline Hoppe , Dongling Li , Christian Latza , Veerle Rottiers , Harald Hutter , Adam Antebi	2013-08-06	nhr-8
23791784	Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Mol. Cell John S Reece-Hoyes , Carles Pons , Alos Diallo , Akihiro Mori , Shaleen Shrestha , Sreenath Kadreppa , Justin Nelson , Stephanie Diprima , Amelie Dricot , Bryan R Lajoie , Philippe Souza Moraes Ribeiro , Matthew T Weirauch , David E Hill , Timothy R Hughes , Chad L Myers , Albertha J M Walhout	2013-07-11	pop-1, lim-7, unc-37, gla-3, ahr-1, nhr-49, aha-1, eya-1, lir-1, nhr-19, mab-3, unc-130, Y53F4B.3, mxl-2, nhr-20, mdt-15, hmg-1.2, T26A5.8, mml-1, pie-1, T26A8.4, zip-7, W03F9.2, nhr-13, unc-62, ceh-34, nhr-47, mxl-1, hif-1, mdl-1, syd-9, ceh-14, nhr-91, nhr-76, tbx-38, pax-3, nhr-181, ces-1, sptf-2, nhr-234, unc-39, ceh-40, nhr-17, ceh-20
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20461074	Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol. Syst. Biol. H Efsun Arda , Stefan Taubert , Lesley T MacNeil , Colin C Conine , Ben Tsuda , Marc Van Gilst , Reynaldo Sequerra , Lynn Doucette-Stamm , Keith R Yamamoto , Albertha J M Walhout	2010-05-11	nhr-109, daf-2, mdt-15, nhr-10, nhr-66, nhr-86, lbp-9, nhr-12, nhr-70, nhr-79, nhr-45, nhr-91, nhr-28, nhr-178, nhr-142, nhr-273, nhr-234, nhr-41
16845399	Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat. Genet. Ben Lehner , Catriona Crombie , Julia Tischler , Angelo Fortunato , Andrew G Fraser	2006-08-01	his-40, egl-30, sop-3, unc-73, let-502, rnt-1, lin-35, gpc-2, swsn-9, pbrm-1, goa-1, ego-1, apr-1, kin-10, unc-120, ceh-6, cdk-8, aph-1, irx-1, sur-6, nhr-49, mom-5, csnk-1, rga-2, gsk-3, pry-1, hmp-2, sur-2, ptr-23, hlh-1, vab-1, tsn-1, fbf-1, fbf-2, rars-2, lin-23, egl-27, cdc-42, lir-1, B0495.2, spv-1, qua-1, jun-1, let-23, ref-1, ptp-3, din-1, trr-1, lin-29, ace-4, unc-52, nhr-80, attf-3, mat-3, swsn-3, nhr-6, mtm-3, cdk-12, ndg-4, mel-28, abi-1, hmg-1.2, algn-1, T26A5.8, ubc-18, lin-37, zfp-1, pat-2, lin-12, glp-1, gei-13, ham-3, pha-1, nob-1, set-16, tpa-1, efn-4, egl-18, ced-10, nstp-6, vab-2, hlh-30, htz-1, eor-1, lag-1, lin-45, nhr-8, F33D4.6, arf-3, hgrs-1, nhr-66, nap-1, pkg-2, F49C12.12, F49C12.11, lin-3, kin-4, let-60, par-5
9851916	Genome sequence of the nematode C. elegans: a platform for investigating biology. Science C. elegans Sequencing Consortium	1998-12-11	-

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