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17755 Map1b

17755

Map1b

microtubule-associated protein 1B

protein-coding

Mus musculus

基因描述

Type Description
Definition microtubule-associated protein 1B

研究结论

Date Results Publications
2020-06-13 12:34:00 MAP 1B phosphorylation sites are specifically involved in axon growth. 31711525
2019-12-14 10:04:00 These data provide independent confirmation in a mouse model with combined PARK1/PARK4/PARK6 pathology that MAP1B/ANK2 phosphorylation events are implicated in Parkinsonian neurodegeneration. 31277379
2019-11-02 11:27:00 Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B 30425305
2018-12-22 11:09:00 Data show that loss of MAP1B function affects general cognitive ability through a profound, brain-wide WM deficit with likely disordered or compromised axons. 30150678
2018-04-14 10:39:00 MAP1B knockout neurons display a decrease in the density of presynaptic and postsynaptic terminals, which involves a reduction in the density of synaptic contacts, and an increased proportion of orphan presynaptic terminals. MAP1B knockout neurons present altered synaptic vesicle fusion events, and a decrease in the density of both synaptic vesicles and dense core vesicles at presynaptic terminals. 27425640

名称对应

Type IDs
Synonymous A230055D22, AI843217, LC1, MAP5, Mtap-5, Mtap1b, Mtap5
Gene
UniProtKB-ID: MAP1B_MOUSE, Q8CFR9_MOUSE, Q3UF78_MOUSE
UniprotKB: P14873, Q8CFR9, Q3UF78
UniParc: UPI0000021C8B, UPI00005AC825, UPI00000E8F8B
EMBL: AC170188, X51396, BC037105, AK148870
Ensembl: ENSMUSG00000052727
KO: mmu:17755
Nucleutide sequences
EMBL-CDS: CAA35761.1, AAH37105.1, BAE28683.1
Ensembl_TRS: ENSMUST00000064762
Protein sequencees
Ensembl_PRO: ENSMUSP00000068374
RefSeq: XP_006517611.1, NP_032660.2
Others
UniRef100: UniRef100_P14873, UniRef100_Q8CFR9
UniRef90: UniRef90_Q8CFR9, UniRef90_P14873
UniRef50: UniRef50_P15205, UniRef50_P14400
UniGene: Mm.4173, Mm.474609, Mm.474896
CCDS: CCDS26723.1

全选

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