| Type | Description |
|---|---|
| Definition | Netrin receptor unc-5 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 10:32:00 | We assume that in these mutants, secretion and stability of various TSR-containing and possibly other proteins are affected. Since impairment of UNC-5 alone is not sufficient for the development of the dumpy phenotype further C-mannosylation-dependent proteins must be involved. | 31868591 |
| 2019-06-01 13:14:00 | abl-1 negatively regulates unc-53 during DTC migrations and requirement of unc-53 function during both AP and DV DTC migrations could be due to unc-53 mediated regulation of unc-5 activity | 28678595 |
| 2016-05-14 12:07:00 | Small GTPases mediate MOM-5's regulation of unc-5 such that one outcome of impaired function of small GTPases like CED-10/Rac and MIG-2/RhoG is an increase in unc-5 function. | 26292279 |
| 2015-01-10 11:16:00 | The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP. | 25371370 |
| 2011-12-03 10:26:00 | UNC-6/netrin, UNC-5 and UNC-40/DCC modulated the extent of growth cone protrusion. Loss-of-function unc-5 mutants displayed increased protrusion in repelled growth cones, whereas loss-of-function unc-6 or unc-40 mutants caused decreased protrusion. | 21880785 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UNC5_CAEEL,
V6CLL7_CAEEL,
V6CLK6_CAEEL,
V6CK86_CAEEL
UniprotKB:
Q26261,
V6CLL7,
V6CLK6,
V6CK86
UniParc:
UPI0000452237,
UPI0003C98912,
UPI00001641AD,
UPI00000809C0,
UPI0003C9E23F
EMBL:
S47166,
S47167,
S47137,
FO080145,
BX284604,
S47134,
S47165,
S47135,
S47136,
S47164,
S47168
EnsemblGenome:
WBGene00006745
KO:
cel:CELE_B0273.4
|
| Nucleutide sequences |
EMBL-CDS:
CCD61589.1,
AAB23866.2,
CCD61588.1,
AAB23867.2,
CDK13452.1,
CDK13453.1,
CDK13451.1
Gene_ORFName:
B0273.4,
B0273.4,
CELE_B0273.4,
B0273.4,
CELE_B0273.4,
B0273.4,
CELE_B0273.4
EnsemblGenome_TRS:
B0273.4a.1,
B0273.4b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
B0273.4a.1,
B0273.4b.1
RefSeq:
NP_500823.1,
NP_500822.2,
NP_001370921.1,
NP_001293749.1,
NP_001368390.1,
NP_001293751.1
|
| Others |
UniRef100:
UniRef100_Q26261
UniRef90:
UniRef90_Q26261
UniRef50:
UniRef50_Q26261
UniGene:
Cel.18168
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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