| Type | Description |
|---|---|
| Definition | Helix Loop Helix |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30. | 32259199 |
| 2020-01-11 10:41:00 | Study shows that C. elegans granulins production increases with age and stress, and granulin expression reduces animal fitness by impairing lysosomal protease expression and activity. This prompts cells to activate a compensatory transcriptional program involving HLH-30/TFEB nuclear translocation and up-regulation of the transcription of HLH-30/TFEB-related genes. | 31398187 |
| 2019-12-21 11:23:00 | A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of C. elegans. | 30299269 |
| 2019-12-21 10:26:00 | HLH-30 activation is critical for sustaining survival during starvation-refeeding stress via regulating TOR. | 31086360 |
| 2019-12-07 11:40:00 | altering the nuclear export of HLH-30/TFEB can regulate autophagy. | 29768192 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
H2KZZ2_CAEEL,
H2KZZ0_CAEEL,
H2KZZ3_CAEEL,
H2KZZ1_CAEEL,
Q86MJ3_CAEEL
UniprotKB:
H2KZZ2,
H2KZZ0,
H2KZZ3,
H2KZZ1,
Q86MJ3
UniParc:
UPI0000185C1D,
UPI0000185C1E,
UPI0000185C20,
UPI0000074949,
UPI000007E497
EMBL:
BX284604
EnsemblGenome:
WBGene00020930
|
| Nucleutide sequences |
EMBL-CDS:
CCD70589.1,
CCD70587.1,
CCD70592.1,
CCD70588.1,
CCD70591.1
Gene_ORFName:
CELE_W02C12.3,
W02C12.3,
W02C12.3,
CELE_W02C12.3,
W02C12.3,
CELE_W02C12.3,
W02C12.3,
CELE_W02C12.3,
W02C12.3,
CELE_W02C12.3
|
| Protein sequencees |
RefSeq:
NP_500461.1,
NP_001023411.1,
NP_001350991.1,
NP_001023414.1,
NP_001370704.1,
NP_001368701.1,
NP_500462.1,
NP_001023413.1,
NP_001360026.1,
NP_001370705.1
|
| Others |
UniRef100:
UniRef100_H2KZZ0,
UniRef100_H2KZZ2,
UniRef100_H2KZZ3,
UniRef100_H2KZZ1
UniRef90:
UniRef90_H2KZZ2,
UniRef90_H2KZZ0
UniRef50:
UniRef50_H2KZZ2
UniGene:
Cel.6901
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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