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177016 lin-1

177016

lin-1

hypothetical protein

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition hypothetical protein

研究结论

Date Results Publications
2018-07-21 11:05:00 we investigate orthologs of a transcription complex that acts in mammalian EGFR signaling-lin-1/Elk1, sur-2/Med23, and the Cdk8 Kinase module (CKM).our analysis using cell fate reporters reveals that both EGFR and LIN-12/Notch signal transduction pathways are active in all VPCs in lin-1/Elk1 mutants 28954762
2015-11-28 10:18:00 A model is proposed in which LIN-1 recruits multiple transcriptional repressors to inhibit the 1 degrees vulval cell fate, and phosphorylation by ERK converts LIN-1 to a transcriptional activator that promotes the 1 degrees vulval cell fate. 25567989
2011-02-26 10:06:00 Data show that loss-of-function mutations of moc-3 and dph-3 effectively suppress the Multivulva (Muv) phenotype of the lin-1(e1275, R175Opal) mutation. 20479142
2010-01-21 00:00:00 lin-1 is required positively for the proper expression of several genes regulated by the pathway in cells adopting the 1 degrees cell fate. 16140291
2010-01-21 00:00:00 lin-39 is a direct target of the Ras pathway acting via LIN-1 and LIN-31 16782085

名称对应

Type IDs
Gene
UniProtKB-ID: G5EDL0_CAEEL, U4PLN0_CAEEL
UniprotKB: G5EDL0, U4PLN0
UniParc: UPI000052CFA8, UPI0000083C97
EMBL: BX284604, U38935, AH003439, U38936
EnsemblGenome: WBGene00002990
KO: cel:CELE_C37F5.1
Nucleutide sequences
EMBL-CDS: AAA93079.1, CCD66965.1, AAB60254.1, CDH93003.1
Gene_ORFName: C37F5.1, CELE_C37F5.1, C37F5.1, CELE_C37F5.1
Protein sequencees
RefSeq: NP_001294301.1, NP_001023051.1
Others
UniRef100: UniRef100_G5EDL0
UniRef90: UniRef90_G5EDL0
UniRef50: UniRef50_G5EDL0
UniGene: Cel.21742

全选

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