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176991 egl-4

176991

egl-4

cGMP-dependent protein kinase;cGMP-dependent protein kinase egl-4;hypothetical protein

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition cGMP-dependent protein kinase;cGMP-dependent protein kinase egl-4;hypothetical protein

研究结论

Date Results Publications
2017-03-25 11:49:00 we provide evidence that the C. elegans transmembrane guanylyl cyclase ODR-1 functions in a non-cell-autonomous manner to provide cGMP to regulate EGL-4 function in ASH 27459302
2014-09-27 12:18:00 Data (including data from studies in mutant and transgenic strains) suggest that stress response to fasting (lysosomal lipid accumulation) is co-ordinately regulated by EGL-4/PKG (protein kinase G) and nuclear hormone receptor NHR-49. 24854345
2014-05-10 12:20:00 Nuclear PKG localization is necessary in the AWB neurons to mediate avoidance in Caenorhabditis elegans. 23954825
2014-01-11 11:15:00 activated EGL-4 dampens quinine sensitivity via phosphorylation and activation of the regulator of G protein signaling (RGS) proteins RGS-2 and RGS-3, which in turn downregulate Galpha signaling and behavioral sensitivity. 23874221
2012-09-29 11:04:00 odor-induced fluctuations in cGMP levels and this fluctuation may be responsible for sending EGL-4 into the AWC nucleus. 22319638

名称对应

Type IDs
Gene
UniProtKB-ID: EGL4_CAEEL, U4PEQ9_CAEEL
UniprotKB: O76360, U4PEQ9
UniParc: UPI0000426199, UPI0000077B1C, UPI000042619A, UPI000002A22A, UPI00000866C3, UPI0003B048DB, UPI000045223B
EMBL: BX284604, FO081473
EnsemblGenome: WBGene00001173
KO: cel:CELE_F55A8.2
Nucleutide sequences
EMBL-CDS: CCD71864.1, CCD71859.1, CCD71862.1, CCD71861.1, CCD71860.1, CCD71863.1, CDH93222.1
Gene_ORFName: F55A8.2, F55A8.2, CELE_F55A8.2
EnsemblGenome_TRS: F55A8.2b.2, F55A8.2c.3, F55A8.2f.1, F55A8.2e.1, F55A8.2c.2, F55A8.2c.1, F55A8.2a.1, F55A8.2a.2, F55A8.2e.2, F55A8.2f.2, F55A8.2d.1, F55A8.2b.1
Protein sequencees
EnsemblGenome_PRO: F55A8.2b.1, F55A8.2d.1, F55A8.2a.2, F55A8.2e.2, F55A8.2f.2, F55A8.2c.2, F55A8.2c.1, F55A8.2a.1, F55A8.2e.1, F55A8.2c.3, F55A8.2f.1, F55A8.2b.2
RefSeq: NP_741330.2, NP_500142.1, NP_500141.1, NP_741329.1, NP_001023223.1, NP_001294450.1, NP_001023224.1, NP_001368271.1
Others
UniRef100: UniRef100_O76360, UniRef100_U4PEQ9
UniRef90: UniRef90_O76360
UniRef50: UniRef50_O76360
UniGene: Cel.38682

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