| Type | Description |
|---|---|
| Definition | E3 ubiquitin-protein ligase parkin;Parkinson's Disease Related;RBR-type E3 ubiquitin transferase |
| Date | Results | Publications |
|---|---|---|
| 2016-02-13 11:44:00 | While no change in mRNA expression of the major Mn importer proteins (smf-1-3) was found in pdr-1 mutants, significant downregulation in mRNA levels of the putative Mn exporter ferroportin (fpn-1.1) was observed. | 25769119 |
| 2015-10-03 10:56:00 | These data show that mutation in the Caenorhabditis elegans orthologue of Parkin (pdr-1) modulates the level of a large heteroplasmic mtDNA truncation. | 25462019 |
| 2014-11-08 12:10:00 | The pdr1 and djr1.1 mutants showed enhanced Mn accumulation and oxidative stress that was reduced by alpha-synuclein. | 24452053 |
| 2014-10-25 10:57:00 | PDR-1 inhibits apoptotic cell engulfment and distal tip cell migration by ubiquitylating CED-10 for degradation. | 24625979 |
| 2010-01-21 00:00:00 | In contrast to pdr-1 loss-of-function mutants, an in-frame parkin homolog pdr-1 deletion variant with altered solubility and intracellular localization properties is hypersensitive toward different proteotoxic stress conditions. | 16204351 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q9XUS3_CAEEL,
V6CLF7_CAEEL
UniprotKB:
Q9XUS3,
V6CLF7
UniParc:
UPI0003C9D174,
UPI00000427AE
EMBL:
BX284603
EnsemblGenome:
WBGene00003967
KO:
cel:CELE_K08E3.7
|
| Nucleutide sequences |
EMBL-CDS:
CAB04599.2,
CDK13444.1
Gene_ORFName:
K08E3.7,
CELE_K08E3.7,
CELE_K08E3.7,
K08E3.7
|
| Protein sequencees |
RefSeq:
NP_001370029.1,
NP_001360308.1,
NP_001293603.1
|
| Others |
UniRef100:
UniRef100_Q9XUS3
UniRef90:
UniRef90_Q9XUS3
UniRef50:
UniRef50_Q9XUS3
UniGene:
Cel.6671
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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