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176758 lis-1

176758

lis-1

Lissencephaly-1 homolog

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Lissencephaly-1 homolog

研究结论

Date Results Publications
2019-04-27 10:16:00 The C. elegans NudE homolog NUD-2 is dispensable for dynein- and LIS-1-dependent mitotic spindle assembly in the zygote. This facilitates functional characterization of kinetochore-localized NUD-2, which is recruited by the CENP-F-like proteins HCP-1 and HCP-2 independently of RZZ-Spindly and dynein-LIS-1. 29192061
2010-01-21 00:00:00 Dynein and Lis1, albeit functioning in identical processes, are targeted partially independently of one another. 15331665
2010-01-21 00:00:00 The convulsions mimicking epilepsy can be induced by a mutation in a C. elegans lis-1 allele (pnm-1), in combination with a chemical antagonist of gamma-aminobutyric acid (GABA) neurotransmitter signaling. 15254012
2010-01-21 00:00:00 lis-1 induces a spindle checkpoint-dependent mitotic arrest in the germline and an increase in germ-cell apoptosis. 17376425

名称对应

Type IDs
Gene
UniProtKB-ID: LIS1_CAEEL
UniprotKB: Q9NDC9
UniParc: UPI000007E1F8
EMBL: Z81113, AF164430
EnsemblGenome: WBGene00003047
KO: cel:CELE_T03F6.5
Nucleutide sequences
EMBL-CDS: AAF82632.1, CAB03282.3
Gene_ORFName: T03F6.5
EnsemblGenome_TRS: T03F6.5.1
Protein sequencees
EnsemblGenome_PRO: T03F6.5.1
RefSeq: NP_499755.1
Others
UniRef100: UniRef100_Q9NDC9
UniRef90: UniRef90_Q9NDC9
UniRef50: UniRef50_Q9NDC9
UniGene: Cel.19492

全选

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研究热度

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