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176597 crh-1

176597

crh-1

CREB Homolog

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition CREB Homolog

研究结论

Date Results Publications
2020-07-04 12:53:00 Removal of this single isoform of creb1/crh-1 shows defects in long-term memory formation in the animal and expression of CREB1/CRH-1e in a single pair of neurons is sufficient to rescue the memory defects seen in the mutant animals 31413073
2018-02-17 10:09:00 Here the authors show that the Caenorhabditis elegans SHN-1/Shank binds L-type calcium channels and that increased and decreased shn-1 gene dosage alter L-channel current and activity-induced expression of a CRH-1/CREB transcriptional target (gem-4 Copine). 28477407
2017-06-24 12:12:00 Both CRH-1 and FLP-6 are necessary and sufficient for longevity at warm temperatures. 27720609
2015-01-24 13:11:00 In Caenorhabditis elegans, the amine neurotransmitter octopamine activates a CREB homolog, CRH-1, in cholinergic SIA neurons, whereas dopamine suppresses CREB activation by inhibiting octopamine signaling in response to food stimuli. 23977320
2013-08-10 10:31:00 crh-1 is essential for long-term memory for context conditioning and habituation. 23013276

名称对应

Type IDs
Gene
UniProtKB-ID: G5ECG1_CAEEL, G5EBL5_CAEEL, Q8I4D8_CAEEL, Q8I4D7_CAEEL, D0Z5N2_CAEEL, Q9U2I0_CAEEL, D0Z5N1_CAEEL
UniprotKB: G5ECG1, G5EBL5, Q8I4D8, Q8I4D7, D0Z5N2, Q9U2I0, D0Z5N1
UniParc: UPI0001BE8B53, UPI0000083B8A, UPI00000860A2, UPI0000083B3D, UPI0000086588, UPI00000860A1, UPI0001BE8B54
EMBL: AB081595, AB081596, BX284603
EnsemblGenome: WBGene00000793
KO: cel:CELE_Y41C4A.4
Nucleutide sequences
EMBL-CDS: BAC19842.1, CAD56256.1, BAC19843.1, CAB54381.2, CAD45607.2, CAD56255.1, CBI63241.1, CAB54382.2, CBI63240.1
Gene_ORFName: Y41C4A.4, CELE_Y41C4A.4, CELE_Y41C4A.4, Y41C4A.4, Y41C4A.4, CELE_Y41C4A.4, CELE_Y41C4A.4, Y41C4A.4, Y41C4A.4, CELE_Y41C4A.4, Y41C4A.4, CELE_Y41C4A.4, Y41C4A.4, CELE_Y41C4A.4
Protein sequencees
RefSeq: NP_001022861.1, NP_001022862.1, NP_001255136.1, NP_001022860.1, NP_001022859.1, NP_001022863.1, NP_001255135.1
Others
UniRef100: UniRef100_G5EBL5, UniRef100_Q9U2I0, UniRef100_Q8I4D8, UniRef100_Q8I4D7, UniRef100_D0Z5N2, UniRef100_G5ECG1, UniRef100_D0Z5N1
UniRef90: UniRef90_D0Z5N1, UniRef90_D0Z5N2, UniRef90_Q8I4D7
UniRef50: UniRef50_D0Z5N2, UniRef50_D0Z5N1, UniRef50_Q8I4D7
UniGene: Cel.19765

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