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176548 tra-1

176548

tra-1

Sex-determining transformer protein 1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Sex-determining transformer protein 1

研究结论

Date Results Publications
2020-03-07 11:08:00 Mutations in tra-1 and goa-1 decouple behavioural patterns from the number of X chromosomes. TRA-1 binds to a conserved binding site located in the goa-1 coding region, and downregulates goa-1 expression in hermaphrodites, particularly during embryogenesis when neuronal development largely occurs. 31776761
2014-07-19 13:02:00 WDR-5.1 associates with the fog-3 promoter and is required for TRA-1 to bind to fog-3 promoter. 24682813
2013-12-07 11:23:00 TRA-1 promotes female development primarily by preventing the expression of genes involved in male development. 24046365
2011-07-16 11:30:00 In the proximal germline, sperm-dependent physiological MPK-1 activation results in phosphorylation-based inactivation of NOS-3, FEM-CUL-2-mediated degradation of TRA-1 and the promotion of membrane organization during oogenesis. 21571224
2010-01-21 13:07:00 The C. elegans p97/CDC-48-UFD-1-NPL-4 complex controls the sperm-oocyte switch by regulating CUL-2-mediated TRA-1A proteasome degradation. 19773360

名称对应

Type IDs
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001022880.2, NP_001022881.2
Others
UniGene: Cel.9756

全选

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研究热度

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