| Type | Description |
|---|---|
| Definition | Protein unc-119 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-27 11:13:00 | The authors demonstrate that ARL-3 is a unique small GTPase with unusual high intrinsic GDP release but low intrinsic GTP binding rate. Importantly, ARL-13 acts as a nucleotide exchange factor (GEF) of ARL-3, while UNC-119 can stabilize the GTP binding of ARL-3. We further show that excess inactivated ARL-3 compromises ciliogenesis. | 27102355 |
| 2017-07-15 10:19:00 | we show that removal of either of two critical P-granule components, PGL-1 or GLH-1, is sufficient to cause germ cells to express UNC-119::GFP and MYO-3 and to display RNA accumulation defects similar to those observed after depletion of P granules. Our data identify P granules as critical modulators of the germline transcriptome and guardians of germ cell fate. | 28258184 |
| 2010-01-21 00:00:00 | Unc-119 mutants result in age-related effects on M2 neurons. | 12885562 |
| 2010-01-21 00:00:00 | UNC-119 function is necessary for the correct development of the Caenorhabditis elegans nervous system | 15892079 |
| 2010-01-21 00:00:00 | the RIBEYE-Munc119 interaction is essential for synaptic transmission at the photoreceptor ribbon synapse. | 18664567 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UN119_CAEEL,
G5EGP9_CAEEL,
C0P283_CAEEL
UniprotKB:
Q10658,
G5EGP9,
C0P283
UniParc:
UPI0001BEB595,
UPI0000482759,
UPI0000137901
EMBL:
BX284603,
Z73428,
U32854
EnsemblGenome:
WBGene00006843
KO:
cel:CELE_M142.1
|
| Nucleutide sequences |
EMBL-CDS:
AAC46919.1,
CAA97807.1,
CBI63231.1,
CAX51683.1
Gene_ORFName:
M142.1,
CELE_M142.1,
M142.1,
CELE_M142.1,
M142.1
EnsemblGenome_TRS:
M142.1a.1
|
| Protein sequencees |
EnsemblGenome_PRO:
M142.1a.1
RefSeq:
NP_001255090.1,
NP_001255088.1,
NP_001255089.1
|
| Others |
UniRef100:
UniRef100_Q10658
UniRef90:
UniRef90_Q10658
UniRef50:
UniRef50_Q10658
UniGene:
Cel.9950
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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