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176506 hpl-2

176506

hpl-2

HP1 Like (heterochromatin protein)

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition HP1 Like (heterochromatin protein)

研究结论

Date Results Publications
2019-06-22 15:09:00 As nuclear involves chromatin changes moderated by HPL-2, a homolog of heterochromatin protein 1 (HP1), we investigated the interaction of TDP-1 and HPL-2. We found that TDP-1 and HPL-2 interact directly and that loss of TDP-1 dramatically alters the chromatin association of HPL-2. 29760282
2015-10-03 11:10:00 At the genic level, HPL-2 preferentially associates with well-expressed genes, and loss of HPL-2 results in up-regulation of some binding targets and down-regulation of others. 25467431
2014-06-21 11:04:00 Caenorhabditis elegans heterochromatin protein like-2 (HPL-2), the homolog of heterochromatin protein 1 (HP1), down-regulates the unfolded protein response in the intestine. 24715729
2012-08-18 11:03:00 The heterochromatin protein 1 family proteins HPL-1 and HPL-2 are dispensable for de novo centromerization even though arrays become strongly enriched for the heterochromatin-associated H3K9me3 modification over time. 22018540
2012-08-18 10:39:00 Caenorhabditis elegans HPL-2 links developmental plasticity, longevity and lipid metabolism. 22185090

名称对应

Type IDs
Gene
UniProtKB-ID: G5EDE2_CAEEL, G5EFS9_CAEEL, Q9U3C6_CAEEL
UniprotKB: G5EDE2, G5EFS9, Q9U3C6
UniParc: UPI000007781E, UPI0000080597, UPI00000789FC
EMBL: BX284603, AF123574, AF123573
EnsemblGenome: WBGene00001996
KO: cel:CELE_K01G5.2
Nucleutide sequences
EMBL-CDS: CAB07241.1, AAD21197.1, CAB07243.2, AAD21196.1, CAB54267.2
Gene_ORFName: K01G5.2, CELE_K01G5.2, K01G5.2, CELE_K01G5.2, CELE_K01G5.2, K01G5.2
Protein sequencees
RefSeq: NP_001022654.1, NP_001022652.1, NP_001022653.1
Others
UniRef100: UniRef100_G5EDE2, UniRef100_G5EFS9, UniRef100_Q9U3C6
UniRef90: UniRef90_G5EDE2, UniRef90_Q9U3C6
UniRef50: UniRef50_G5EDE2, UniRef50_Q9U3C6
UniGene: Cel.10365

全选

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