| Type | Description |
|---|---|
| Definition | G-protein regulator 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-06 13:17:00 | Four distinct in vivo phosphorylated LIN-5 residues were found to have critical functions in spindle positioning. Two of these residues form part of a 30 amino acid binding site for GPR-1, which we identified by reverse two-hybrid screening. These LIN-5 phosphorylations promote LIN-5-GPR-1/2 interaction and contribute to cortical pulling forces | 27711157 |
| 2011-08-27 12:17:00 | Data demonstrate that GPB-1 depletion results in the loss of GPR-1/2 asymmetry during mitosis. | 21652650 |
| 2010-01-21 00:00:00 | Data suggest a mechanism in which RIC-8 favors generation of Galpha free from Gbetagamma and enables GPR-1/2 to mediate asymmetric cell division. | 15479639 |
| 2010-01-21 00:00:00 | Dynamic localization of gpr-2 to cell cortex forces generation of domains during spindle positioning. | 18234174 |
| 2010-01-21 00:00:00 | findings show that the GoLoco-containing proteins GPR-1 and GPR-2, as well as the Galpha subunits GOA-1 and GPA-16, were essential for generation of proper pulling forces in asymmetric spindle positioning | 12750478 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GPR2_CAEEL
UniprotKB:
Q03569
UniParc:
UPI000004E823
EMBL:
Z19153
EnsemblGenome:
WBGene00001689
KO:
cel:CELE_C38C10.4
|
| Nucleutide sequences |
EMBL-CDS:
CAA79548.1
Gene_ORFName:
C38C10.4
EnsemblGenome_TRS:
C38C10.4.1
|
| Protein sequencees |
EnsemblGenome_PRO:
C38C10.4.1
RefSeq:
NP_499066.1
|
| Others |
UniRef100:
UniRef100_Q03569
UniRef90:
UniRef90_Q95QJ7
UniRef50:
UniRef50_Q95QJ7
UniGene:
Cel.23377
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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