| Type | Description |
|---|---|
| Definition | Glutamate receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-01-12 10:24:00 | Low concentrations of quinine are decoded in interneuron AIB by low-threshold, fast-inactivation glutamate receptor GLR-1 and translated into reversal initiation. In contrast, high concentrations of quinine are decoded by high-threshold, slow-inactivation glutamate receptor GLR-5 | 30333484 |
| 2017-05-27 11:24:00 | We also assessed ionotropic glutamate receptor GLR-1 cell-specifically within AIB and determined that GLR-1 fine-tunes AIB activity to modify locomotion following reversal events. Our research highlights that signal integration underlying the initiation and fine-tuning of backwards locomotion is AIB and NPR-9 dependent, and has demonstrated the suitability of C. elegans for analysis of multisensory integration | 27223098 |
| 2017-03-25 11:50:00 | We propose a model in which synaptic activity regulates the nuclear localization of CMK-1 to mediate a negative feedback mechanism coupling GLR-1 activity with its own transcription. | 27462879 |
| 2016-12-17 10:24:00 | Mutants lacking p38 MAPK components pmk-1 or sek-1 resemble mutants lacking the hypoxia response component and prolyl hydroxylase egl-9, with impaired subcellular localization of Mint orthologue LIN-10, internalization of glutamate receptor GLR-1, and depression of GLR-1-mediated behaviors. | 26731517 |
| 2016-07-28 13:00:00 | KEL-8 is a substrate receptor for Cullin 3 ubiquitin ligases that is required for the proteolysis of GLR-1 receptors and suggest a novel postmitotic role in neurons for Kelch/CUL3 ubiquitin ligases. | 16394099 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GLR1_CAEEL
UniprotKB:
P34299
UniParc:
UPI0000001B23
EMBL:
U34661,
FO080280
EnsemblGenome:
WBGene00001612
KO:
cel:CELE_C06E1.4
|
| Nucleutide sequences |
EMBL-CDS:
CCD62564.1,
AAA92006.1
Gene_ORFName:
C06E1.4
EnsemblGenome_TRS:
C06E1.4.1
|
| Protein sequencees |
EnsemblGenome_PRO:
C06E1.4.1
RefSeq:
NP_498887.2
|
| Others |
UniRef100:
UniRef100_P34299
UniRef90:
UniRef90_P34299
UniRef50:
UniRef50_P34299
UniGene:
Cel.6005
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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