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176068 lin-39

176068

lin-39

Homeobox protein lin-39

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Homeobox protein lin-39

研究结论

Date Results Publications
2017-06-03 10:05:00 the HOX protein LIN-39 regulates the vulval precursor cell cycle at two levels. First, LIN-39 acts as a permissive factor by maintaining the expression of the cell cycle machinery in the vulval precursor cells, keeping them competent to proliferate. Second, LIN-39 triggers the lateral NOTCH signaling pathway in the adjacent 2 degrees vulval precursor cells, which over comes the cell cycle inhibition by LIN-31 Forkhead. 27475488
2017-05-27 11:25:00 Here we describe a nonautonomous role of mab-5 in regulating both QR and QL descendant migrations, a role masked by redundancy with lin-39 A third Hox gene, egl-5/Abdominal-B, also likely nonautonomously regulates Q descendant migrations.We find that increased levels of MAB-5 in body wall muscle (BWM) can drive the spon-1 promoter adjacent to the Q cells, and 27225683
2014-10-04 11:45:00 Data indicate that the hypodermal fate regulator LIN-26, and the GATA factor ELT-6 positively regulate lin-39 expression in the embryonic precursors to the Vulval (VPCs). 24885717
2013-09-28 11:14:00 LIN-39 establishes neuroblast anterior polarity by binding to the mig-13 promoter and promoting mig-13 expression, whereas MAB-5 inhibits neuroblast anterior polarity by associating with the lin-39 promoter and downregulating lin-39 and mig-13 expression. 23784779
2011-12-31 10:39:00 Data show that the C. elegans hox gene lin-39 regulates epidermal morphogenesis via its novel target, the essential zinc finger protein VAB-23. 21989912

名称对应

Type IDs
Gene
UniProtKB-ID: LIN39_CAEEL
UniprotKB: P34684
UniParc: UPI000012E66E
EMBL: L19639, L19248, FO080423
EnsemblGenome: WBGene00003024
KO: cel:CELE_C07H6.7
Nucleutide sequences
EMBL-CDS: CCD63594.1, AAB04137.1, AAC37168.1
Gene_ORFName: C07H6.7
EnsemblGenome_TRS: C07H6.7.2, C07H6.7.1
Protein sequencees
EnsemblGenome_PRO: C07H6.7.1, C07H6.7.2
RefSeq: NP_001021164.1
Others
UniRef100: UniRef100_P34684
UniRef90: UniRef90_P34684
UniRef50: UniRef50_P34684
UniGene: Cel.19645

全选

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