| Type | Description |
|---|---|
| Definition | Mediator of RNA polymerase II transcription subunit 15 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | Lipid metabolic sensors of MDT-15 and SBP-1 regulated the response to simulated microgravity in the intestine of Caenorhabditis elegans. | 32448509 |
| 2020-03-07 11:52:00 | Data show that mdt-15 and hizr-1 cooperate to regulate cadmium detoxification and zinc storage and that this mechanism is at least partially conserved in mammals. | 31815936 |
| 2020-02-29 10:48:00 | Authors show that dietary supplementation with a monounsaturated fatty acid, oleic acid (OA), substantially mitigates the short life span and proteotoxicity in mdt-15(-) animals at low temperatures. Thus, lipidostasis regulated by MDT-15 appears to be a limiting factor for proteostasis and longevity at low temperatures. | 31408455 |
| 2016-07-16 10:34:00 | AAK-2 regulates oxidative metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 transcriptional regulators. | 26824904 |
| 2016-04-02 10:29:00 | sterol regulatory element-binding protein (SREBP) and mediator-15 (MDT-15) prevent the life-shortening effects of a glucose-rich diet by regulating fat-converting processes in Caenorhabditis elegans | 26637528 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MED15_CAEEL
UniprotKB:
Q21955
UniParc:
UPI000013BB72,
UPI000004E834
EMBL:
FO081686
EnsemblGenome:
WBGene00007016
KO:
cel:CELE_R12B2.5
|
| Nucleutide sequences |
EMBL-CDS:
CCD73316.1,
CCD73317.1
Gene_ORFName:
R12B2.5
EnsemblGenome_TRS:
R12B2.5a.1,
R12B2.5b.2,
R12B2.5b.1,
R12B2.5a.2
|
| Protein sequencees |
EnsemblGenome_PRO:
R12B2.5a.1,
R12B2.5b.2,
R12B2.5b.1,
R12B2.5a.2
RefSeq:
NP_001370818.1,
NP_741151.1
|
| Others |
UniRef100:
UniRef100_Q21955
UniRef90:
UniRef90_Q21955
UniRef50:
UniRef50_Q21955
UniGene:
Cel.38778
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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