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175802 wrm-1

175802

wrm-1

Armadillo repeat-containing protein wrm-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Armadillo repeat-containing protein wrm-1

研究结论

Date Results Publications
2015-05-02 12:15:00 Our data support a model in which WRM-1, which can undergo homotypic interaction, binds LIT-1 and thereby generates a kinase complex in which LIT-1 molecules are situated in a conformation enabling autophosphorylation. 25548171
2013-05-04 12:33:00 model in which Wnt signaling and CDK-1 modify WRM-1 in a temporal and spatial manner to unmask an intrinsic polarity cue required for proper orientation of the endomesoderm cell division axis 23431196
2011-11-26 10:35:00 SYS-1 and POP-1 nuclear levels are regulated in opposite directions; the C terminus of POP-1 is essential for LIT-1 phosphorylation and is specifically bound by the diverged beta-catenin WRM-1 21852394
2011-11-12 10:55:00 Study shows that during telophase of an asymmetric division in C. elegans, extrinsic Wnt signaling modulates spindle structures through APR-1/APC, which in turn promotes asymmetrical nuclear localization of WRM-1/beta-catenin and POP-1/TCF. 21925317
2011-01-01 11:14:00 Animals with reduced function of the beta-catenins SYS-1 and WRM-1 have as few as three seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells. 20849842

名称对应

Type IDs
Gene
UniProtKB-ID: WRM1_CAEEL, A0A0K3AUT2_CAEEL
UniprotKB: Q10953, A0A0K3AUT2
UniParc: UPI000007CFA5, UPI0005CDCFBE
EMBL: BX284603, AF013951, FO080138
EnsemblGenome: WBGene00006943
KO: cel:CELE_B0336.1
Nucleutide sequences
EMBL-CDS: CCD61515.1, AAC47748.1, CTQ86556.1
Gene_ORFName: B0336.1, CELE_B0336.1, B0336.1
EnsemblGenome_TRS: B0336.1a.1, B0336.1a.2
Protein sequencees
EnsemblGenome_PRO: B0336.1a.2, B0336.1a.1
RefSeq: NP_498236.1, NP_001299856.1
Others
UniRef100: UniRef100_Q10953
UniRef90: UniRef90_Q10953
UniRef50: UniRef50_Q10953
UniGene: Cel.16964

全选

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