| Type | Description |
|---|---|
| Definition | Cell surface receptor daf-4;Receptor protein serine/threonine kinase;Serine/threonine-protein kinase receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:24:00 | TSP-12 and TSP-14 are required for the recycling of DAF-4/BMPRII. | 31988138 |
| 2020-02-08 11:27:00 | Our mutant daf-4 nematode models of Marfan syndrome (MFS) suggest that MFS and MFS-like mutations in the TGFB type II receptor lead to mis-trafficking of the receptor and possibly provides an explanation for the disease, a phenomenon which might also occur in some cancers that possess the same mutations within the type II receptor (e.g. colon cancer). | 31071172 |
| 2010-01-21 00:00:00 | alternative polyadenylation in intron 5 of daf-4 results in a 2.0 kb mRNA that encodes an open reading frame including only the N-terminal secretion signal and ligand-binding domains, and not the transmembrane or kinase domains | 15254038 |
| 2010-01-21 00:00:00 | isolated dauer-formation mutations in C. briggsae, a species closely related to the model organism C. elegans and identified mutations in orthologs of C. elegans genes daf-2, daf-3 and daf-4 | 17660533 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DAF4_CAEEL,
G8JY02_CAEEL,
A0A131MB12_CAEEL,
Q8ITX8_CAEEL,
A0A131MBJ8_CAEEL
UniprotKB:
P50488,
G8JY02,
A0A131MB12,
Q8ITX8,
A0A131MBJ8
UniParc:
UPI000005C927,
UPI00077FE5E3,
UPI0000002DF4,
UPI00077FE57F,
UPI000005C925
EMBL:
BX284603,
L23110
EnsemblGenome:
WBGene00000900
KO:
cel:CELE_C05D2.1
|
| Nucleutide sequences |
EMBL-CDS:
AAA03544.1,
CCD63118.1,
CCD63120.1,
CZR14508.1,
CCD63119.1,
CZR14507.1
Gene_ORFName:
C05D2.1,
CELE_C05D2.1,
C05D2.1,
C05D2.1,
CELE_C05D2.1,
CELE_C05D2.1,
C05D2.1,
C05D2.1,
CELE_C05D2.1
EnsemblGenome_TRS:
C05D2.1a.1,
C05D2.1a.2
|
| Protein sequencees |
EnsemblGenome_PRO:
C05D2.1a.1,
C05D2.1a.2
RefSeq:
NP_001021148.1,
NP_001309588.1,
NP_001021149.1,
NP_498211.1,
NP_001317770.1
|
| Others |
UniRef100:
UniRef100_P50488,
UniRef100_G8JY02,
UniRef100_A0A131MB12
UniRef90:
UniRef90_G8JY02,
UniRef90_P50488
UniRef50:
UniRef50_G8JY02,
UniRef50_P50488
UniGene:
Cel.6349
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员