| Type | Description |
|---|---|
| Definition | Progestin and AdipoQ Receptor family |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:37:00 | We conclude that acs-13 mutations in C. elegans and ACSL1 knockdown in human cells prevent lipotoxicity by promoting increased levels of polyunsaturated fatty acid-containing phospholipids | 31769755 |
| 2019-07-13 11:14:00 | The Caenorhabditis elegans adiponectin receptor AdipoR2 homolog PAQR-2 signaling detects temperature drop and augments the biosynthesis of two omega-6 polyunsaturated fatty acids, gamma-linolenic acid and arachidonic acid. These two polyunsaturated fatty acids in turn initiate autophagy in the epidermis, delaying an age-dependent decline in collagen contents, and extending the lifespan. | 31197136 |
| 2017-10-14 11:07:00 | We conclude that the PAQR-2 and AdipoR2 proteins share an evolutionarily conserved function that maintains membrane fluidity in the presence of exogenous saturated fatty acids. | 28886012 |
| 2016-08-20 10:15:00 | PAQR-2 and IGLR-2 interact on plasma membranes and thus may act together as a fluidity sensor that controls membrane lipid composition. | 27082444 |
| 2014-03-22 11:05:00 | This model is supported by the observations that the paqr-2 suppressors normalize the levels of saturated fatty acids, and that low concentrations of detergents that increase membrane fluidity can rescue the paqr-2 mutant. | 24068966 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q9N536_CAEEL
UniprotKB:
Q9N536
UniParc:
UPI00001B29EF
EMBL:
BX284603
EnsemblGenome:
WBGene00021313
KO:
cel:CELE_Y32H12A.5
|
| Nucleutide sequences |
EMBL-CDS:
CCD73963.1
Gene_ORFName:
Y32H12A.5,
CELE_Y32H12A.5
|
| Protein sequencees |
RefSeq:
NP_498148.2
|
| Others |
UniRef100:
UniRef100_Q9N536
UniRef90:
UniRef90_Q9N536
UniRef50:
UniRef50_Q9N536
UniGene:
Cel.17644
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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