| Type | Description |
|---|---|
| Definition | 5-demethoxyubiquinone hydroxylase, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 10:40:00 | Loss of ubiquinone biosynthesis is responsible for all phenotypes resulting from loss of CLK-1, including behavioral phenotypes, altered expression of mitochondrial quality control genes, and lifespan. | 28404998 |
| 2015-09-05 11:01:00 | Nuclear CLK-1 mediates a retrograde signalling pathway that is conserved from Caenorhabditis elegans to humans and is responsive to mitochondrial reactive oxygen species, thus acting as a barometer of oxidative metabolism. | 25961505 |
| 2011-12-10 10:26:00 | no measurable intrinsic ETC defect exists in clk-1 mitochondria. The data indicate that DMQ(9) specifically inhibits electron transfer from complex I to ubiquinone. | 21745495 |
| 2010-01-21 00:00:00 | Prolonged life span of Clk mutants cannot be attributed to reduced metabolic rate or an increased activity of the major antioxidant enzymes catalase and SOD. | 12425951 |
| 2010-01-21 00:00:00 | Caenorhabditis elegans clk-1 mutants are sensitive to ubiquinone side-chain length | 12893826 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
COQ7_CAEEL
UniprotKB:
P48376
UniParc:
UPI0000127F03
EMBL:
FO080775
EnsemblGenome:
WBGene00000536
KO:
cel:CELE_ZC395.2
|
| Nucleutide sequences |
EMBL-CDS:
CCD66658.1
Gene_ORFName:
ZC395.2
EnsemblGenome_TRS:
ZC395.2.1
|
| Protein sequencees |
EnsemblGenome_PRO:
ZC395.2.1
RefSeq:
NP_498128.1
|
| Others |
UniRef100:
UniRef100_P48376
UniRef90:
UniRef90_P48376
UniRef50:
UniRef50_P48376
UniGene:
Cel.10672
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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