| Type | Description |
|---|---|
| Definition | Splicing Factor ThreeB (3b) Subunit homolog |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:05:00 | Study reproduced three cancer-related SF3B1 missense mutations in the C. elegans ortholog sftb-1 and they do not cause any overt phenotypes, but few alterations in splicing. However, the combination of these mutations has additive effects, hampering SFTB-1 functions and allowing the study of synthetic interactions that may result in a defective spliceosome structure. | 31634348 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G5EEQ8_CAEEL
UniprotKB:
G5EEQ8
UniParc:
UPI000006110D
EMBL:
BX284603
EnsemblGenome:
WBGene00011605
KO:
cel:CELE_T08A11.2
|
| Nucleutide sequences |
EMBL-CDS:
CAA90777.1
Gene_ORFName:
CELE_T08A11.2,
T08A11.2
|
| Protein sequencees |
RefSeq:
NP_497853.1
|
| Others |
UniRef100:
UniRef100_G5EEQ8
UniRef90:
UniRef90_G5EEQ8
UniRef50:
UniRef50_O75533
UniGene:
Cel.17612
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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