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17535 Mre11a

17535

Mre11a

MRE11A homolog A, double strand break repair nuclease

protein-coding

Mus musculus

基因描述

Type Description
Definition MRE11A homolog A, double strand break repair nuclease

研究结论

Date Results Publications
2020-05-16 12:14:00 We propose that XLF and H2AX function in series to prevent replication stress induced by the MRE11-dependent resection of regressed arms at reversed replication forks. 31123184
2020-04-04 11:13:00 Nbn-Mre11 interaction is required for tumor suppression and genomic integrity. 31285322
2019-10-19 12:35:00 MRE11 disease-associated splice mutation leads to low protein levels and cellular mislocalization. 29973640
2017-11-25 15:12:00 the essential role of Nbs1 is via its interaction with Mre11 and that most of the Nbs1 protein is dispensable for Mre11 complex functions and suggest that Mre11 and Rad50 directly activate ATM. 28076792
2017-10-28 13:20:00 Low MRE11 expression is associated with B-cell lymphomas. 28819025

名称对应

Type IDs
Synonymous Mre11, Mre11b
Gene
UniProtKB-ID: MRE11_MOUSE, Q8BRV3_MOUSE, Q3TU24_MOUSE, Q3URU4_MOUSE
UniprotKB: Q61216, Q8BRV3, Q3TU24, Q3URU4
UniParc: UPI0000023914, UPI00000EAD8B, UPI00005B1CC9, UPI000002AE4C
EMBL: AK041248, AK161013, AK141214, U58987, U60318, BC065144
Ensembl: ENSMUSG00000031928
KO: mmu:17535
Nucleutide sequences
EMBL-CDS: AAH65144.1, AAB03664.1, AAB04955.1, BAC30878.1, BAE36147.1, BAE24593.1
Ensembl_TRS: ENSMUST00000034405, ENSMUST00000115632
Protein sequencees
Ensembl_PRO: ENSMUSP00000034405, ENSMUSP00000111295
RefSeq: XP_030099943.1, XP_006510111.1, XP_036010537.1, XP_006510117.1, NP_061206.1, XP_006510114.1, XP_036010536.1, XP_006510112.1, XP_006510116.1, NP_001297657.1
Others
UniRef100: UniRef100_Q61216
UniRef90: UniRef90_Q61216
UniRef50: UniRef50_Q61216
UniGene: Mm.149071
CCDS: CCDS22827.1, CCDS80958.1

全选

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