| Type | Description |
|---|---|
| Definition | myelin protein zero |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | Upregulation of large myelin protein zero leads to Charcot-Marie-Tooth disease-like neuropathy in mice. | 32170207 |
| 2017-09-16 11:21:00 | Data show that both transgenic Wnt1-cre and P0-cre are similarly effective in deleting beta-catenin in the neural crest. | 27184910 |
| 2016-10-22 12:18:00 | In the absence of P0, thus, PLP also contributes to myelination by Schwann cells and to the preservation of peripheral axons | 26393339 |
| 2016-04-23 10:43:00 | interaction with neurofascins impaired by mutations D6Y, D32G, and H52Y responsible for late onset forms of the human disease | 26406915 |
| 2015-09-26 21:31:00 | while PLP can co-exist with P0 in peripheral nervous system(PNS) myelin, PLP cannot replace P0 as the major structural protein of PNS myelin. | 25066805 |
| Type | IDs |
|---|---|
| Synonymous | Mpp, P-zero, P0 |
| Gene |
UniProtKB-ID:
MYP0_MOUSE,
E9QK82_MOUSE,
A0A5F8MPM4_MOUSE
UniprotKB:
P27573,
E9QK82,
A0A5F8MPM4
UniParc:
UPI00001EDEB9,
UPI0000020EE2,
UPI00000041C9
EMBL:
AK157960,
BC139139,
M62860,
AK089180,
M62859,
BC141226,
CH466520,
M62857,
M62858,
AC163497
Ensembl:
ENSMUSG00000056569
KO:
mmu:17528
|
| Nucleutide sequences |
EMBL-CDS:
AAI39140.1,
EDL39129.1,
AAI41227.1,
BAE34285.1,
EDL39131.1,
BAC40781.1,
AAA39867.1
Ensembl_TRS:
ENSMUST00000111334,
ENSMUST00000238940,
ENSMUST00000070758,
ENSMUST00000238908
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106966,
ENSMUSP00000066701,
ENSMUSP00000159043,
ENSMUSP00000159037
RefSeq:
NP_001302429.1,
NP_032649.2,
NP_001302428.1
|
| Others |
UniRef100:
UniRef100_P27573,
UniRef100_A0A5F8MPM4
UniRef90:
UniRef90_P25189,
UniRef90_P27573
UniRef50:
UniRef50_P27573,
UniRef50_P25189
UniGene:
Mm.9986
CCDS:
CCDS15479.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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