| Type | Description |
|---|---|
| Definition | myeloperoxidase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:26:00 | Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro. | 32050431 |
| 2020-05-30 13:05:00 | The study showed that when MPO activity is either blocked by the specific inhibitor 4-aminobenzoic acid hydrazide (ABAH) in wildtype (WT) mice or congenitally absent (MPO(-/-)), there was decreased cell loss, including degenerating neurons and oligodendrocytes, in the ischemic brains compared to vehicle-treated WT mice after stroke. | 29673284 |
| 2019-12-14 11:22:00 | These data suggest that MPO inhibition does not alter atherosclerotic plaque area or leukocyte homing, but rather alters the inflammatory tone of atherosclerotic lesions; thus, MPO inhibition could have utility to promote atherosclerotic lesion stabilization and prevent atherosclerotic plaque rupture. | 30889221 |
| 2019-07-27 12:58:00 | MPO, via ionic interaction with heparan sulfate side chains, can cause neutrophil-dependent Sdc1 shedding and collapse of the endothelial glycocalyx structure. | 29903730 |
| 2018-04-14 10:06:00 | Severe clinical and pathological disease is associated with the induction of anti-MPO IgG/LPS-mediated glomerulonephritis. | 28186568 |
| Type | IDs |
|---|---|
| Synonymous | mKIAA4033 |
| Gene |
UniProtKB-ID:
PERM_MOUSE,
Q7TMS4_MOUSE,
Q571G0_MOUSE
UniprotKB:
P11247,
Q7TMS4,
Q571G0
UniParc:
UPI0000021935,
UPI00001AA212,
UPI00004FF401
EMBL:
AK220229,
AL604022,
X15313,
X15378,
BC053912
Ensembl:
ENSMUSG00000009350
KO:
mmu:17523
|
| Nucleutide sequences |
EMBL-CDS:
CAA33439.1,
CAA33373.1,
AAH53912.1,
BAD90154.1
Ensembl_TRS:
ENSMUST00000020779,
ENSMUST00000121303
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020779,
ENSMUSP00000112837
RefSeq:
NP_034954.2
|
| Others |
UniRef100:
UniRef100_Q571G0,
UniRef100_Q7TMS4,
UniRef100_P11247
UniRef90:
UniRef90_P11247
UniRef50:
UniRef50_P11247
UniGene:
Mm.4668
CCDS:
CCDS25217.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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