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175121 arl-3

175121

arl-3

ADP-ribosylation factor-like protein 3

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition ADP-ribosylation factor-like protein 3

研究结论

Date Results Publications
2018-01-27 11:13:00 The authors demonstrate that ARL-3 is a unique small GTPase with unusual high intrinsic GDP release but low intrinsic GTP binding rate. Importantly, ARL-13 acts as a nucleotide exchange factor (GEF) of ARL-3, while UNC-119 can stabilize the GTP binding of ARL-3. We further show that excess inactivated ARL-3 compromises ciliogenesis. 27102355
2010-07-12 11:10:00 Data suggest that two conserved small GTPases, ARL-13 and ARL-3, coordinate to regulate intraflagellar transport and that perturbing this balance results in cilia deformation. 20530210

名称对应

Type IDs
Gene
UniProtKB-ID: ARL3_CAEEL
UniprotKB: O45379
UniParc: UPI000007652E
EMBL: Z93378
EnsemblGenome: WBGene00000188
KO: cel:CELE_F19H8.3
Nucleutide sequences
EMBL-CDS: CAB07583.1
Gene_ORFName: F19H8.3
EnsemblGenome_TRS: F19H8.3.1
Protein sequencees
EnsemblGenome_PRO: F19H8.3.1
RefSeq: NP_497037.1
Others
UniRef100: UniRef100_O45379
UniRef90: UniRef90_O45379
UniRef50: UniRef50_O45379
UniGene: Cel.17800

全选

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研究热度

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