| Type | Description |
|---|---|
| Definition | C-type lectin domain family 4, member d |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection. | 32540868 |
| 2017-11-04 11:35:00 | MCL (macrophage C-type lectin) plays a crucial role in killing bacteria during Escherichia coli-induced peritonitis. MCL-deficient mice with E. coli-induced sepsis showed lower survival rates and reduced bacterial clearance when compared with control mice, despite similar levels of proinflammatory cytokine production. | 28988116 |
| 2017-08-12 11:05:00 | Dectin-3 deficiency did not lead to increased susceptibility of mice to experimental pulmonary C. neoformans infection. Also, no significant differences in pulmonary leukocyte recruitment and cytokine production were observed in Dectin-3 deficient mice compared to wild type infected mice | 28107361 |
| 2017-07-29 10:21:00 | activation of CLRs Dectin-2 and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk-dependent manner. | 27432944 |
| 2017-05-06 13:18:00 | The authors report that microbial stimulation triggers Mincle (Clec4e) expression through the myeloid differentiation primary response gene 88 (MyD88) pathway; a process that does not require MCL (Clecsf8, Clec4d). Conversely, they show that MCL is constitutively expressed but retained intracellularly until Mincle is induced, whereupon the receptors form heterodimers which are translocated to the cell surface. | 27005451 |
| Type | IDs |
|---|---|
| Synonymous | Clecsf8, Mpcl, mcl |
| Gene |
UniProtKB-ID:
CLC4D_MOUSE,
Q4KL29_MOUSE,
Q3UBK0_MOUSE
UniprotKB:
Q9Z2H6,
Q4KL29,
Q3UBK0
UniParc:
UPI00000233DF,
UPI00005ACA66
EMBL:
AK171409,
AK150926,
AK089500,
BC099471,
AF061272
Ensembl:
ENSMUSG00000030144
KO:
mmu:17474
|
| Nucleutide sequences |
EMBL-CDS:
AAD05125.1,
BAC40905.1,
BAE42436.1,
AAH99471.1,
BAE29964.1
Ensembl_TRS:
ENSMUST00000032240
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032240
RefSeq:
NP_034949.3,
NP_001156633.1
|
| Others |
UniRef100:
UniRef100_Q9Z2H6,
UniRef100_Q3UBK0
UniRef90:
UniRef90_Q9Z2H6
UniRef50:
UniRef50_Q9Z2H6
UniGene:
Mm.441101
CCDS:
CCDS20513.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员