| Type | Description |
|---|---|
| Definition | CD200 antigen |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:58:00 | Study detected in vivo and in vitro effect of the CD200 protein on psoriasis and on co-cultured macrophages and keratinocytes. Expression of CD200 and CD200R1 was decreased and the expression of macrophage-related pro-inflammatory factors was increased in imiquimod-induced psoriasis-like mouse skin, suggesting that CD200-CD200R1 signaling can reduce skin inflammation by inhibiting the activation of macrophages. | 31835080 |
| 2020-06-06 11:51:00 | Neuronal CD200 upregulation significantly improve cognitive function. Specific elevated CD200 in neuron not alter amyloid plaque formation. Neuronal CD200 upregulation prevent microglial activation induced synaptic dysfunction. | 31277944 |
| 2020-03-28 10:34:00 | CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease | 31790427 |
| 2020-03-21 11:39:00 | The results provided evidence that the expression changes of CD200-CD200R1 axis were highly correlated with neovascularization in retina. Activation of this axis showed strong anti-inflammatory and anti-angiogenic effects in an oxygen-induced retinopathy model, which revealed a new potential therapeutic target for retinal neovascularization treatment. | 31444514 |
| 2019-10-26 10:57:00 | blockade of the endogenous ligand CD200 prevented the tumorigenic effect of CD200R-expressing myeloid cells in the tumor microenvironment, whereas agonistic anti-CD200R has no effect on tumor development | 30653571 |
| Type | IDs |
|---|---|
| Synonymous | Mox2, OX2 |
| Gene |
UniProtKB-ID:
Q80VX2_MOUSE
UniprotKB:
Q80VX2
UniParc:
UPI000019267B
EMBL:
BC051984,
AC117783,
BC054759,
AC117686
Ensembl:
ENSMUSG00000022661
|
| Nucleutide sequences |
EMBL-CDS:
AAH51984.1,
AAH54759.1
Ensembl_TRS:
ENSMUST00000163230
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000130518
RefSeq:
NP_001345372.1,
XP_017172379.1,
NP_034948.3
|
| Others |
UniRef100:
UniRef100_Q80VX2
UniRef90:
UniRef90_O54901
UniRef50:
UniRef50_P41217
UniGene:
Mm.245851
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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