| Type | Description |
|---|---|
| Definition | Tar DNA-binding protein homolog 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-22 15:09:00 | As nuclear involves chromatin changes moderated by HPL-2, a homolog of heterochromatin protein 1 (HP1), we investigated the interaction of TDP-1 and HPL-2. We found that TDP-1 and HPL-2 interact directly and that loss of TDP-1 dramatically alters the chromatin association of HPL-2. | 29760282 |
| 2016-04-30 10:58:00 | TDP-1 regulates lifespan and proteotoxicity through DAF-16. | 25329970 |
| 2015-07-25 11:10:00 | These data show that the primary function of TDP-1, an ortholog of the neurodegeneration-associated RNA-binding protein TDP-43, is to limit formation or stability of double-stranded RNA. | 25391662 |
| 2014-01-18 12:24:00 | It causes age-dependent toxicity to motor neurons. | 23591130 |
| 2012-09-29 11:07:00 | These results suggest that chronic induction of wild-type TDP-1/TDP-43 by cellular stress may propagate neurodegeneration and decrease lifespan. | 22792076 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TADBP_CAEEL
UniprotKB:
D0VWM8
UniParc:
UPI000007B9F1,
UPI0000253F25,
UPI00004B6E7C
EMBL:
BX284602
EnsemblGenome:
WBGene00006514
KO:
cel:CELE_F44G4.4
|
| Nucleutide sequences |
EMBL-CDS:
CBH29662.1,
CAA90120.1,
CAH04715.1
Gene_ORFName:
F44G4.4
EnsemblGenome_TRS:
F44G4.4a.1,
F44G4.4c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F44G4.4c.1,
F44G4.4a.1
RefSeq:
NP_001022166.1,
NP_001254189.1
|
| Others |
UniRef100:
UniRef100_D0VWM8
UniRef90:
UniRef90_D0VWM8
UniRef50:
UniRef50_D0VWM8
UniGene:
Cel.15106
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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