| Type | Description |
|---|---|
| Definition | Serine/threonine-protein kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:29:00 | Alleviating chronic ER stress by p38-Ire1-Xbp1 pathway and insulin-associated autophagy in C. elegans neurons. | 32986702 |
| 2020-01-11 10:39:00 | Authors show that autophagy is modulated through the conserved IRE-1-XBP-1 axis, strongly suggesting of the importance of autophagy in maintaining cellular homeostasis during the lipid bilayer stress-induced UPR. | 30333136 |
| 2017-11-25 15:41:00 | vitamin-D3-induced lifespan extension requires the stress response pathway genes skn-1, ire-1, and xbp-1. | 27783938 |
| 2017-10-21 10:31:00 | Enhanced study of the role of IIS pathway and epigenetic mechanisms that regulate aging may facilitate progressive prevention and treatment of human age-related diseases. | 28101820 |
| 2017-09-02 11:48:00 | IRE-1 has an ancient function as a cytoplasmic sentinel that activates p38 and SKN-1(Nrf2). csteine modifications induced by signals can direct proteins to adopt unexpected functions and may coordinate many cellular processes. | 27540856 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IRE1_CAEEL,
E5QCG0_CAEEL
UniprotKB:
Q09499,
E5QCG0
UniParc:
UPI0001F40D6E,
UPI000007FFB4
EMBL:
Z48045,
AF435952,
BX284602
EnsemblGenome:
WBGene00002147
KO:
cel:CELE_C41C4.4
|
| Nucleutide sequences |
EMBL-CDS:
AAL30828.1,
CAA88100.2,
CBY24252.1
Gene_ORFName:
C41C4.4,
C41C4.4,
CELE_C41C4.4
EnsemblGenome_TRS:
C41C4.4a.1
|
| Protein sequencees |
EnsemblGenome_PRO:
C41C4.4a.1
RefSeq:
NP_001254136.1,
NP_001254135.1
|
| Others |
UniRef100:
UniRef100_Q09499
UniRef90:
UniRef90_Q09499
UniRef50:
UniRef50_Q09499
UniGene:
Cel.24223
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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