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17425 Foxk1

17425

Foxk1

forkhead box K1

protein-coding

Mus musculus

基因描述

Type Description
Definition forkhead box K1

研究结论

Date Results Publications
2020-05-30 13:18:00 The siRNA-mediated repression of vimentin in FOXK1-overexpressing cells reversed the epithelial-mesenchymal transition -like phenotype and reduced Gastric Cancer cell migration and invasion in vitro and in vivo. 30483822
2019-12-28 10:38:00 Knockdown of FoxK1 in primary hepatocytes decreased both glucose production and insulin's ability to suppress it. The findings expand the repertoire of insulin-dependent transcription factors and identify FoxK1 as a contributor to insulin signaling. 30936148
2019-07-27 10:42:00 in vitro and in vivo experiments, including studies of primary human cells, show how FOXK1 and/or FOXK2 are likely to act as important regulators that reprogram cellular metabolism to induce aerobic glycolysis 30700909
2019-05-11 12:19:00 FoxK1/K2 are reciprocally regulated to FoxO1 following insulin stimulation and play a critical role in the control of apoptosis, metabolism and mitochondrial function. 30952843
2019-03-09 11:15:00 Foxk1 mediates mTORC1-driven metabolic rewiring, and it is likely to be critical for metabolic diseases where improper mTORC1 signaling plays an important role. 29861159

名称对应

Type IDs
Synonymous A630048H08Rik, AI463295, Gm10868, Mnf
Gene
UniProtKB-ID: FOXK1_MOUSE
UniprotKB: P42128
UniParc: UPI00005AC643
EMBL: AK147375, L26507, AK144418, U95016
Ensembl: ENSMUSG00000056493
KO: mmu:17425
Nucleutide sequences
EMBL-CDS: BAE25880.1, BAE27871.1, AAA37529.1, AAB69641.1
Ensembl_TRS: ENSMUST00000072837
Protein sequencees
Ensembl_PRO: ENSMUSP00000072616
RefSeq: NP_951031.2, XP_006504717.1
Others
UniRef100: UniRef100_P42128
UniRef90: UniRef90_P42128
UniRef50: UniRef50_P42128
UniGene: Mm.24214
CCDS: CCDS19826.1

全选

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研究热度

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