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17423 Ndst2

17423

Ndst2

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2

protein-coding

Mus musculus

基因描述

Type Description
Definition N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2

研究结论

Date Results Publications
2019-02-09 10:30:00 An essential role for Heparin sulfate proteoglycan sulfation via NDST1,2,3 in modulating signal transduction during mouse implantation. 29688404
2017-05-20 14:54:00 Size estimation of heparan sulfate polysaccharide chains indicated that increased chain lengths in NDST2-overexpressing cells alone could explain the increased heparan sulfate content. A model is discussed where NDST2-specific substrate modification stimulates elongation resulting in increased heparan sulfate chain length. 27387504
2012-09-22 11:17:00 embryonic stem cells lacking both NDST1 and NDST2, expressing a very low sulfated heparan sulfate, can take the initial step toward differentiation into all three germ layers 22298785
2010-01-21 00:00:00 NDST1 and NDST2 have roles in N-sulfation but not in 6-O-sulfation of heparan sulfate 15319440
2010-01-21 00:00:00 NDST-2 does not contribute significantly to tissue-specific Heparan Sulfate structures 15292174

名称对应

Type IDs
Synonymous Mndns, NDST-2
Gene
UniProtKB-ID: NDST2_MOUSE
UniprotKB: P52850
UniParc: UPI0000000997
EMBL: AK150100, X75885, BC110480, U02304, AF074925
Ensembl: ENSMUSG00000039308
KO: mmu:17423
Nucleutide sequences
EMBL-CDS: AAI10481.1, AAD15979.1, CAA53479.1, AAC52137.1, BAE29307.1
Ensembl_TRS: ENSMUST00000047490, ENSMUST00000225000, ENSMUST00000223679
Protein sequencees
Ensembl_PRO: ENSMUSP00000040227, ENSMUSP00000153036, ENSMUSP00000153141
RefSeq: XP_030103542.1, NP_034941.2
Others
UniRef100: UniRef100_P52850
UniRef90: UniRef90_P52850
UniRef50: UniRef50_P52850
UniGene: Mm.4084
CCDS: CCDS26854.1

全选

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