Type | Description |
---|---|
Definition | Kinesin-like protein unc-104 |
Date | Results | Publications |
---|---|---|
2017-11-18 13:44:00 | Synaptic vesicle bound small GTPase ARL-8 activates UNC-104 by unlocking the autoinhibition. The results demonstrate that the autoinhibitory mechanism is utilized to regulate the distribution of transport cargoes and is important for synaptogenesis in vivo. | 27524618 |
2017-10-21 12:17:00 | LIN-2 and SYD-2 both positively affect the velocity of UNC-104 | 27172328 |
2017-06-24 12:46:00 | findings indicate that autophagy is spatially regulated in neurons through the transport of ATG-9 by KIF1A/UNC-104 to regulate neurodevelopment | 27396362 |
2017-01-14 10:07:00 | Reduced function of UNC-104 accelerates motor circuit dysfunction with age, whereas upregulation of UNC-104 significantly improves motor function at advanced ages and also mildly extends lifespan. In addition, UNC-104-overexpressing animals outperform wild-type controls in associative learning and memory tests. | 26877087 |
2013-08-31 10:16:00 | This study establishes an essential role of the CC1-FHA dimer for KIF1A/unc-104-mediated neuronal transport. | 23669038 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
UN104_CAEEL
UniprotKB:
P23678
UniParc:
UPI0002995CBB,
UPI000016430C
EMBL:
BX284602,
M58582
EnsemblGenome:
WBGene00006831
KO:
cel:CELE_C52E12.2
|
Nucleutide sequences |
EMBL-CDS:
AAA03517.1,
CCD64622.2,
CCD64623.2
Gene_ORFName:
C52E12.2
EnsemblGenome_TRS:
C52E12.2a.1,
C52E12.2b.1,
C52E12.2b.2,
C52E12.2a.2
|
Protein sequencees |
EnsemblGenome_PRO:
C52E12.2a.2,
C52E12.2a.1,
C52E12.2b.1,
C52E12.2b.2
RefSeq:
NP_741019.3,
NP_001022041.2
|
Others |
UniRef100:
UniRef100_P23678
UniRef90:
UniRef90_P23678
UniRef50:
UniRef50_P23678
UniGene:
Cel.5126
|
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