| Type | Description |
|---|---|
| Definition | Probable Werner syndrome ATP-dependent helicase homolog 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 10:50:00 | WRN-1 plays a conserved role in the resection of DSB ends and mediates checkpoint signaling, thereby influencing levels of RPA and RAD-51 | 28640365 |
| 2016-10-22 10:24:00 | WRN-1 functions downstream of RPA-1 and upstream of CHK-1 in the DSB checkpoint pathway and is also required for the repair of DSB. | 26691982 |
| 2012-04-14 10:48:00 | analysis of physical and functional interactions of Caenorhabditis elegans WRN-1 helicase with RPA-1 | 22257160 |
| 2010-03-29 12:01:00 | WRN-1 functions together with RPA-1 upstream of ATM and ATR to trigger cell cycle arrest in response to double-strand DNA breaks. | 20062519 |
| 2010-01-21 00:00:00 | WRN-1 acts as a checkpoint protein for DNA damage and replication blockage. | 15115755 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
WRN_CAEEL
UniprotKB:
Q19546
UniParc:
UPI0000086655
EMBL:
FO080970
EnsemblGenome:
WBGene00006944
KO:
cel:CELE_F18C5.2
|
| Nucleutide sequences |
EMBL-CDS:
CCD68193.1
Gene_ORFName:
F18C5.2
EnsemblGenome_TRS:
F18C5.2.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F18C5.2.1
RefSeq:
NP_495324.2
|
| Others |
UniRef100:
UniRef100_Q19546
UniRef90:
UniRef90_Q19546
UniRef50:
UniRef50_Q19546
UniGene:
Cel.7245
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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