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174050 lgg-1

174050

lgg-1

Protein lgg-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Protein lgg-1

研究结论

Date Results Publications
2020-03-07 11:31:00 LGG-1 is involved in the exposure of the 'eat-me signal' phosphatidylserine at the surface of the apoptotic cell to allow its recognition by the phagocytic cell, whereas LGG-2 is involved in later steps of phagocytosis to allow efficient cell corpse clearance by mediating the maturation/degradation of the phagosome. 30160610
2020-02-29 10:05:00 While the molecular basis for the accumulation of lipidated and nonlipidated LGG-1 in atg-18 mutants remains unclear, starvation-induced increases in the nonlipidated form suggest that C. elegans boosts levels of lipidated LGG-1 by supplying more nonlipidated substrate, rather than by rendering phosphatidylethanolamine conjugation more efficient. 30910027
2019-06-29 10:32:00 This work analyzed in apoptotic cell and phagocytic cell the localization of the two homologs of LC3/GABARAP proteins, namely, LGG-1 and LGG-2. 30610704
2016-04-30 10:22:00 Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins. 26687600
2014-03-22 11:44:00 During allophagy LGG-1 acts upstream of LGG-2 to allow its localization to autophagosomes. 24374177

名称对应

Type IDs
Gene
UniProtKB-ID: LGG1_CAEEL
UniprotKB: Q09490
UniParc: UPI000013BEE7
EMBL: AF326943, BX284602
EnsemblGenome: WBGene00002980
KO: cel:CELE_C32D5.9
Nucleutide sequences
EMBL-CDS: CCD66037.1, AAG49393.1
Gene_ORFName: C32D5.9
EnsemblGenome_TRS: C32D5.9.1
Protein sequencees
EnsemblGenome_PRO: C32D5.9.1
RefSeq: NP_495277.1
Others
UniRef100: UniRef100_Q09490
UniRef90: UniRef90_Q09490
UniRef50: UniRef50_Q09490
UniGene: Cel.23297

全选

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