| Type | Description |
|---|---|
| Definition | matrix metallopeptidase 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Long-term plasticity of inhibitory synapses in the hippocampus and spatial learning depends on matrix metalloproteinase 3. | 32959071 |
| 2020-03-07 10:30:00 | MMP-3 regulates cutaneous collagen degradation under inflammatory conditions. | 31652545 |
| 2020-01-04 11:31:00 | Study in transgenic mice found that barrier breakdown and expression of inflammatory factors contribute to development of serrated polyps. Subsets of cecal PDGFRA+ fibroblasts are activated by release of Il1b from myeloid cells during the early stages of serrated polyp development. Mmp3 produced by PDGFRA+ fibroblasts is important for serrated polyp development. | 31470007 |
| 2019-10-26 12:11:00 | Targeted knockdown of MMP3 attenuates proliferation, migration, and invasion of the metastatic adenocarcinoma cells. Nuclear PEX domain/MMP3 localized in primary tumor-stroma marginal area and lung-metastatic tumor nodules. | 29761931 |
| 2019-10-26 10:12:00 | Thrombin exclusively induced MCP-1 via the MAPK-ERK and PI3K-AKT pathways. MCP-1 produced by mIVDs induced macrophage migration and thrombin treatment increased MMP-3 production to induce mIVD degeneration. These effects of thrombin on mIVDs were abrogated by a PAR1 inhibitor and suggest that thrombin may be a novel factor capable of stimulating cytokine activity implicated in the regulation several aspects of mIVDs | 30054581 |
| Type | IDs |
|---|---|
| Synonymous | EMS-2, MMP-3, SL-1, SLN-1, SLN1, STR-1, Stmy1, Str1 |
| Gene |
UniProtKB-ID:
MMP3_MOUSE,
Q3UFJ0_MOUSE,
Q922W6_MOUSE
UniprotKB:
P28862,
Q3UFJ0,
Q922W6
UniParc:
UPI00005AC7E8,
UPI000000D6FF,
UPI0000028FFA
EMBL:
AC115689,
BC006725,
X66402,
X63162,
AY211543,
AK148467
Ensembl:
ENSMUSG00000043613
KO:
mmu:17392
|
| Nucleutide sequences |
EMBL-CDS:
CAA47029.1,
CAA44860.1,
BAE28570.1,
AAH06725.1,
AAO37583.1
Ensembl_TRS:
ENSMUST00000034497
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034497
RefSeq:
NP_034939.1
|
| Others |
UniRef100:
UniRef100_P28862,
UniRef100_Q3UFJ0
UniRef90:
UniRef90_P28862
UniRef50:
UniRef50_P03957
UniGene:
Mm.4993
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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