| Type | Description |
|---|---|
| Definition | matrix metallopeptidase 24 |
| Date | Results | Publications |
|---|---|---|
| 2016-05-28 10:52:00 | MT5-MMP emerges as a new pro-amyloidogenic regulator of APP metabolism, whose deficiency alleviates amyloid pathology, neuroinflammation and cognitive decline. | 26202697 |
| 2016-04-30 11:24:00 | APP carboxy-terminal fragment generation is mediated in part by membrane-bound matrix metalloproteinases such as MT5-MMP, referred to as eta-secretase activity | 26322584 |
| 2014-09-06 12:22:00 | identify MT5-MMP as a membrane-type metalloproteinase responsible for the shedding of the N-cadherin ectodomain in this niche | 24952463 |
| 2010-01-21 00:00:00 | Findings demonstrate an essential role of MT5-MMP in the development of dermal neuro-immune synapses and suggest that this metalloproteinase may be a target for pain control. | 19805319 |
| 2010-01-21 00:00:00 | MT5-MMP retrieval to the plasma membrane is regulated by Mint-3 by binding to its carboxyl end motif EWV | 14990567 |
| Type | IDs |
|---|---|
| Synonymous | AU040325, MMP-21, MT5-MMP, MT5MMP, MTMMP5 |
| Gene |
UniProtKB-ID:
MMP24_MOUSE
UniprotKB:
Q9R0S2
UniParc:
UPI00003561EA
EMBL:
AL929233,
AB021226,
AJ010262
Ensembl:
ENSMUSG00000027612
KO:
mmu:17391
|
| Nucleutide sequences |
EMBL-CDS:
CAA09055.1,
BAA82966.1
Ensembl_TRS:
ENSMUST00000029141
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029141
RefSeq:
NP_034938.3,
XP_030104072.1
|
| Others |
UniRef100:
UniRef100_Q9R0S2
UniRef90:
UniRef90_Q9R0S2
UniRef50:
UniRef50_Q9R0S2
UniGene:
Mm.330707,
Mm.389325
CCDS:
CCDS16955.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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