| Type | Description |
|---|---|
| Definition | afadin, adherens junction formation factor |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | Afadin regulates actomyosin organization through alphaE-catenin at adherens junctions. | 32227204 |
| 2020-12-26 13:12:00 | Disruption of the nectin-afadin complex recapitulates features of the human cleft lip/palate syndrome CLPED1. | 32554531 |
| 2020-08-29 12:49:00 | mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division. | 32581239 |
| 2020-05-02 11:46:00 | Afadin binding with interaction partners in adipocytes, among which HDAC6 preferentially interacts with phosphorylated Afadin and acts as a key intermediate to suppress insulin receptor protein levels. | 31264358 |
| 2020-02-15 13:25:00 | These results demonstrate a novel function for hepatic AF6 in the regulation of insulin sensitivity. | 31127058 |
| Type | IDs |
|---|---|
| Synonymous | 5033403D15Rik, AF6, Af-6, Afadin, Gm314, I-afadin, Mllt4, S-afadin |
| Gene |
UniProtKB-ID:
AFAD_MOUSE,
E9Q9C3_MOUSE
UniprotKB:
Q9QZQ1,
E9Q9C3
UniParc:
UPI0000D67CFF,
UPI0001565427,
UPI00015058D3
EMBL:
AF172447,
AK016557,
CT030652,
CAAA01106165,
AC155253,
CAAA01218165,
CAAA01201738,
CAAA01134612,
AC174800
Ensembl:
ENSMUSG00000068036
KO:
mmu:17356
|
| Nucleutide sequences |
EMBL-CDS:
AAD54283.1
Ensembl_TRS:
ENSMUST00000150848,
ENSMUST00000139666,
ENSMUST00000137784
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000122447,
ENSMUSP00000118318,
ENSMUSP00000119153
RefSeq:
XP_006523818.1,
XP_030105388.1,
XP_006523821.1,
XP_006523825.1,
XP_006523822.1,
XP_006523819.1,
XP_006523823.1,
XP_036016241.1,
XP_006523828.1,
XP_030105386.1,
XP_006523816.1,
XP_036016240.1,
XP_006523817.1,
XP_006523827.1,
XP_017172764.1,
XP_006523830.1,
XP_006523826.1,
XP_006523815.1,
XP_006523820.1,
XP_006523829.1,
XP_017172765.1,
XP_030105387.1,
NP_034936.1
|
| Others |
UniRef100:
UniRef100_E9Q9C3,
UniRef100_Q9QZQ1
UniRef90:
UniRef90_P55196-3,
UniRef90_O35889
UniRef50:
UniRef50_P55196-1,
UniRef50_O35889
UniGene:
Mm.59167
CCDS:
CCDS49955.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员