| Type | Description |
|---|---|
| Definition | mutL homolog 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:42:00 | Exposure to IR accelerated T-cell lymphoma induction in the Mlh1-/- mice. | 30721949 |
| 2019-02-02 11:20:00 | Cancer preceding changes are already seen in histologically normal colon mucosa and that decreased expressions of Mlh1. | 29701748 |
| 2017-08-05 11:16:00 | a causal relationship between MLH1-deficiency and incidence of oncogenic point mutations in tyrosine kinases driving cell transformation and acquired resistance to kinase-targeted cancer therapies, is reported. | 27436342 |
| 2017-05-27 10:25:00 | high mutation ofMlh1(-/-)-deficient fetuses has little effect on the fetuses during their early developmental stages, whereas Mlh1(-/-)-deficient fetuses from X-ray irradiated mothers are clearly effected | 27643877 |
| 2015-06-20 12:48:00 | radiation exposure could further increase the risk of colorectal carcinogenesis induced by inflammation under the conditions of Mlh1 deficiency. | 25529563 |
| Type | IDs |
|---|---|
| Synonymous | 1110035C23Rik, AI317206, AI325952, AI561766 |
| Gene |
UniProtKB-ID:
MLH1_MOUSE
UniprotKB:
Q9JK91
UniParc:
UPI00001F6EFD
EMBL:
AK168849,
U59884,
AF250844,
U60872,
U59882,
U59883,
U59881
Ensembl:
ENSMUSG00000032498
KO:
mmu:17350
|
| Nucleutide sequences |
EMBL-CDS:
AAC52672.1,
BAE40671.1,
AAF64514.1
Ensembl_TRS:
ENSMUST00000035079
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035079
RefSeq:
XP_036010533.1,
XP_006512011.1,
XP_036010532.1,
XP_006512014.1,
NP_001311451.1,
XP_011241237.1,
XP_036010531.1,
XP_036010529.1,
XP_030099939.1,
NP_081086.2,
XP_036010530.1
|
| Others |
UniRef100:
UniRef100_Q9JK91
UniRef90:
UniRef90_Q9JK91
UniRef50:
UniRef50_P40692
UniGene:
Mm.486383
CCDS:
CCDS40784.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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