| Type | Description |
|---|---|
| Definition | MAP kinase-interacting serine/threonine kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 11:21:00 | phosphorylation pattern of eIF4E responds faithfully to Rapamycin inhibition, the prolonged exposure to Rapamycin rescues the loss of eIF4E phosphorylation through Mnk1 activation. | 31782083 |
| 2017-07-22 11:48:00 | MNK1 participates in mediating high-fat diet-induced insulin resistance. Our findings reveal distinct roles for the MNKs in a novel area of disease biology | 27087055 |
| 2017-05-06 11:31:00 | data suggest a physiological role for MNK1a-Ser(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E phosphorylation in vitro and in vivo. | 27413184 |
| 2015-07-25 10:57:00 | Mnk1 is a novel pancreatic acinar cell-specific stress response kinase that regulates digestive enzyme abundance and eIF4E phosphorylation. | 25037190 |
| 2015-07-25 10:36:00 | Long-term potentiation (LTP) consolidation in the dentate gyrus of live rodents requires sustained (hours) BDNF-TrkB signaling and from TrkB to MAP-kinase-interacting kinase. | 25453757 |
| Type | IDs |
|---|---|
| Synonymous | 2410048M24Rik, Mnk1 |
| Gene |
UniProtKB-ID:
MKNK1_MOUSE,
A2A8W8_MOUSE,
Q3U1I8_MOUSE
UniprotKB:
O08605,
A2A8W8,
Q3U1I8
UniParc:
UPI000019090D,
UPI00005ACF95,
UPI00000216EA
EMBL:
AK155934,
BC021369,
Y11091,
AL627085
Ensembl:
ENSMUSG00000028708
KO:
mmu:17346
|
| Nucleutide sequences |
EMBL-CDS:
CAA71965.1,
AAH21369.1,
BAE33509.1
Ensembl_TRS:
ENSMUST00000106513,
ENSMUST00000019677
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102123,
ENSMUSP00000019677
RefSeq:
XP_006502885.1,
XP_036019679.1,
NP_001272416.1,
XP_006502888.1,
NP_001356167.1,
XP_036019678.1,
NP_067436.1,
XP_030109148.1,
NP_001342103.1,
NP_001272417.1,
XP_036019677.1
|
| Others |
UniRef100:
UniRef100_Q3U1I8,
UniRef100_O08605
UniRef90:
UniRef90_O08605
UniRef50:
UniRef50_Q9BUB5
UniGene:
Mm.209327
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员