| Type | Description |
|---|---|
| Definition | iodothyronine deiodinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:34:00 | High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus. | 33232364 |
| 2020-07-18 10:44:00 | The results obtained in the present study indicate that DIO2 polymorphisms rs1352815 and rs1388382 were correlated with KBD susceptibility among Tibetans, which also sheds new light on the role of DIO2 in the development of KBD. | 31433532 |
| 2020-05-23 10:57:00 | Our results indicate that increased thyroidal D1 and D2 activities may be responsible for the higher serum FT3/FT4 ratio in patients with huge goitrous Hashimoto's thyroiditis. | 30737677 |
| 2020-02-29 10:29:00 | 5730A>T mutation of DIO2 decreased selenocysteine-insertion sequence element read-through by 75% | 30423129 |
| 2019-12-14 12:17:00 | This study demonstrated that DIO2 levels were higher in the patients with chronic obstructive pulmonary disease than in the control subjects. | 30978267 |
| Type | IDs |
|---|---|
| Synonymous | 5DII, D2, DIOII, SelY, TXDI2 |
| Gene |
UniProtKB-ID:
IOD2_HUMAN,
A8K845_HUMAN
UniprotKB:
Q92813,
A8K845
UniParc:
UPI0000D48771,
UPI0000169502,
UPI00016428C1,
UPI0000161B1B
EMBL:
U53506,
BC074882,
AL049837,
AB041844,
AC007372,
BC136514,
AB041843,
AK292210,
AC010849,
AF093774
Ensembl:
ENSG00000211448
KO:
hsa:1734
|
| Nucleutide sequences |
EMBL-CDS:
AAC50663.1,
AAH74882.1,
AAI36515.1,
BAB16838.1,
AAC95470.1,
BAB16839.1,
AAD45494.1,
BAF84899.1
Ensembl_TRS:
ENST00000438257,
ENST00000557010
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000405854,
ENSP00000451419
RefSeq:
NP_000784.3,
NP_001311391.2,
NP_054644.1,
NP_001353425.1
|
| Others |
UniRef100:
UniRef100_Q92813
UniRef90:
UniRef90_Q92813
UniRef50:
UniRef50_Q92813
UniGene:
Hs.202354,
Hs.708526,
Hs.732170
CCDS:
CCDS45146.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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