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173345 sur-2

173345

sur-2

Mediator of RNA polymerase II transcription subunit 23

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Mediator of RNA polymerase II transcription subunit 23

研究结论

Date Results Publications
2018-07-21 11:05:00 we investigate orthologs of a transcription complex that acts in mammalian EGFR signaling-lin-1/Elk1, sur-2/Med23, and the Cdk8 Kinase module (CKM).our analysis using cell fate reporters reveals that both EGFR and LIN-12/Notch signal transduction pathways are active in all VPCs in lin-1/Elk1 mutants 28954762
2017-07-29 11:56:00 Study shows that sur-2 mutation affects the Cbr-sur-2/MED23 gene that is orthologous to a C. elegans gene critical for the normal response to the EGF signal. whereas Cel-sur-2 mutants exhibit a reduced vulval development because of defects in the VPC immediately adjacent to the anchor cell (the P6.p cell), similar defects in Caenorhabditis briggsae -sur-2 mutants do not have the same impact. 28220250

名称对应

Type IDs
Gene
UniProtKB-ID: MED23_CAEEL
UniprotKB: Q10669
UniParc: UPI0000136234, UPI000002B466
EMBL: U33051, Z92834
EnsemblGenome: WBGene00006349
KO: cel:CELE_F39B2.4
Nucleutide sequences
EMBL-CDS: CAB07385.2, AAA85507.1, CAB07394.2
Gene_ORFName: F39B2.4
EnsemblGenome_TRS: F39B2.4a.1, F39B2.4b.1
Protein sequencees
EnsemblGenome_PRO: F39B2.4b.1, F39B2.4a.1
RefSeq: NP_001021463.1, NP_493575.2
Others
UniRef100: UniRef100_Q10669
UniRef90: UniRef90_Q10669
UniRef50: UniRef50_Q10669
UniGene: Cel.19738

全选

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