| Type | Description |
|---|---|
| Definition | Beta-catenin-like protein hmp-2 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-14 13:05:00 | Deletion analysis based on the crystal structure shows that the first helix of HMP-1 is necessary for binding HMP-2 avidly in vitro and for efficient recruitment of HMP-1 to adherens junctions in embryos. HMP-2 Ser-47 and Tyr-69 flank its binding interface with HMP-1, and we show that phosphomimetic mutations at these two sites decrease binding affinity of HMP-1 to HMP-2 by 40-100-fold | 28842483 |
| 2017-07-15 11:54:00 | HMP-1 bound filamentous actin with an affinity in the single micromolar range, even when complexed with the beta-catenin homolog HMP-2 or when present in a complex of HMP-2 and the cadherin homolog HMR-1, indicating that HMP-1 binding to F-actin is not allosterically regulated by the HMP-2.HMR-1 complex. | 28298447 |
| 2011-09-10 12:10:00 | The beta-catenin HMP-2 functions downstream of Src in parallel with the Wnt pathway in early embryogenesis of C. elegans. | 21575624 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HMP2_CAEEL,
H2L2I2_CAEEL
UniprotKB:
O44326,
H2L2I2
UniParc:
UPI0000082583,
UPI0002380C50
EMBL:
AF016853,
BX284601,
Z81564
EnsemblGenome:
WBGene00001979
KO:
cel:CELE_K05C4.6
|
| Nucleutide sequences |
EMBL-CDS:
CAB04572.1,
AAB94552.1,
CCE71280.1
Gene_ORFName:
K05C4.6,
K05C4.6,
CELE_K05C4.6
EnsemblGenome_TRS:
K05C4.6a.2,
K05C4.6a.1
|
| Protein sequencees |
EnsemblGenome_PRO:
K05C4.6a.2,
K05C4.6a.1
RefSeq:
NP_001252425.1,
NP_001252426.1
|
| Others |
UniRef100:
UniRef100_O44326
UniRef90:
UniRef90_O44326
UniRef50:
UniRef50_O44326
UniGene:
Cel.7074
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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