| Type | Description |
|---|---|
| Definition | O-6-methylguanine-DNA methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:06:00 | Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure. | 31853708 |
| 2018-06-09 11:17:00 | This study shows that when cell death and cell cycle arrest pathways are inhibited, p53 can still mediate MGMT-dependent repair, to promote cell survival upon DNA damage. | 28753207 |
| 2017-06-10 10:13:00 | Snell, GHKRO, and PAPPA-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT) and N-myc downstream-regulated gene 1 (NDRG1). | 27618784 |
| 2016-01-16 10:45:00 | This study demonstrates for the first time a non-linear dose-response for alkylation-induced colorectal carcinogenesis and reveals DNA repair by MGMT, but not AAG, as a key node in determining a carcinogenic threshold. | 26243310 |
| 2012-12-22 10:44:00 | Findings suggest that O6-methylguanine-DNA methyltransferase (MGMT)-mediated temozolomide resistance is associated with increased histone acetylation. | 22675172 |
| Type | IDs |
|---|---|
| Synonymous | AGT, AI267024, Agat |
| Gene |
UniProtKB-ID:
MGMT_MOUSE,
Q4VA39_MOUSE
UniprotKB:
P26187,
Q4VA39
UniParc:
UPI00005198B6,
UPI0000001683
EMBL:
BC031888,
AB092490,
BC096557,
M84524,
AB092489
Ensembl:
ENSMUSG00000054612
KO:
mmu:17314
|
| Nucleutide sequences |
EMBL-CDS:
AAH31888.1,
BAC16764.1,
AAA37126.1,
BAC16763.1,
AAH96557.1
Ensembl_TRS:
ENSMUST00000081510
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080224
RefSeq:
NP_032624.1,
XP_006507468.1,
XP_006507469.1,
NP_001363966.1,
XP_036008634.1,
XP_006507472.1,
XP_006507470.1,
XP_006507471.1
|
| Others |
UniRef100:
UniRef100_P26187,
UniRef100_Q4VA39
UniRef90:
UniRef90_P26187,
UniRef90_P24528
UniRef50:
UniRef50_P26187,
UniRef50_P24528
UniGene:
Mm.440219
CCDS:
CCDS21945.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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