| Type | Description |
|---|---|
| Definition | Partitioning defective protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:34:00 | Epidermal PAR-6 and are essential for larval development of C. elegans and organize non-centrosomal microtubules. | 33300872 |
| 2017-05-13 22:32:00 | we find that vab-1 lies in the same genetic pathway as cdc-42 and is responsible for polarizing CDC-42 activity to the medial tip. Together, these data establish a previously uncharacterized role for polarized CDC-42, in conjunction with PAR-6, PAR-3 and an Eph receptor(vab-1), during epithelial intercalation. | 27861585 |
| 2016-02-06 10:14:00 | Our results support a model in which CYB-2.1/2/CDK-1 antagonize CUL-2 activity to promote stabilization of PAR-6 levels during polarization of the early C. elegans embryo. | 25658117 |
| 2015-09-12 10:56:00 | the arcade cell epithelium polarizes by a PAR-6-mediated pathway that is independent of E-cadherin, beta-integrin and beta-laminin. | 25773364 |
| 2013-03-23 11:53:00 | PAR-3 and PAR-6 function in cytokinesis may be partially redundant and play a role in the maintenance of DYN-1 in the cleavage furrow. | 22887994 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PAR6_CAEEL
UniprotKB:
Q9NAN2
UniParc:
UPI000007D532,
UPI00006E220F
EMBL:
Z82053,
AF070968
EnsemblGenome:
WBGene00003921
KO:
cel:CELE_T26E3.3
|
| Nucleutide sequences |
EMBL-CDS:
AAD15926.1,
CAB61018.2,
CAJ85768.1
Gene_ORFName:
T26E3.3
EnsemblGenome_TRS:
T26E3.3a.2,
T26E3.3a.1,
T26E3.3b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T26E3.3a.2,
T26E3.3a.1,
T26E3.3b.1
RefSeq:
NP_001040687.1,
NP_001040688.1
|
| Others |
UniRef100:
UniRef100_Q9NAN2
UniRef90:
UniRef90_Q9NAN2
UniRef50:
UniRef50_Q9NAN2
UniGene:
Cel.8562
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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