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17313 Mgp

17313

Mgp

matrix Gla protein

protein-coding

Mus musculus

基因描述

Type Description
Definition matrix Gla protein

研究结论

Date Results Publications
2021-02-27 13:46:00 Matrix Gla protein regulates adipogenesis and is serum marker of visceral adiposity. 32000575
2020-02-08 11:54:00 Observations establish, for the first time, that MGP plays an essential role in osteoclast differentiation and function. The molecular evidence indicates that MGP controls osteoclastogenesis via modulation of the intracellular calcium flux and Src/Rac1 signaling. 30988158
2017-07-22 10:55:00 We propose MGP as a strong candidate for the regulation of stiffness in glaucoma. MGP further illustrates the presence of a common function affecting key glaucomatous parameters in the front and back of the eye, and thus offers the possibility for a sole therapeutic target for the disease. 27593913
2017-07-15 11:39:00 the nasal septum to be abnormally mineralized and shortened in Mgp(-/-) mice. Transgenic restoration of Mgp expression in chondrocytes fully corrected the craniofacial anomalies caused by MGP deficiency, suggesting a local role for MGP in the developing nasal septum. 28487368
2016-10-01 10:36:00 loss of MGP causes dysregulation of early endothelial differentiation. 26364300

名称对应

Type IDs
Synonymous Mglap
Gene
UniProtKB-ID: MGP_MOUSE
UniprotKB: P19788
UniParc: UPI0000003F34
EMBL: AK018719, BC036991, D00613, S77350
Ensembl: ENSMUSG00000030218
KO: mmu:17313
Nucleutide sequences
EMBL-CDS: BAA00488.1, AAP31997.1, BAB31365.1, AAH36991.1
Ensembl_TRS: ENSMUST00000032342
Protein sequencees
Ensembl_PRO: ENSMUSP00000032342
RefSeq: NP_032623.1
Others
UniRef100: UniRef100_P19788
UniRef90: UniRef90_P19788
UniRef50: UniRef50_P08494
UniGene: Mm.243085
CCDS: CCDS20659.1

全选

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研究热度

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