| Type | Description |
|---|---|
| Definition | Mitogen-activated protein kinase kinase kinase dlk-1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 11:12:00 | Complete morphological regeneration depends on DLK-1 but neuronal sprouting and outgrowth is DLK-1 independent. We show that touch receptor neuron(TRN) regeneration is fully functional since animals regain their ability to respond to mechanical stimulation. | 30640919 |
| 2017-07-29 11:49:00 | Mitochondrial localization to the axon after injury is regulated in part by dual-leucine zipper kinase 1 (DLK-1), a conserved regulator of axon regeneration. | 28009276 |
| 2017-03-25 10:18:00 | DLK-1, SEK-3 and PMK-3 have roles in C. elegans adaptation to disruption of the mitochondrial electron transport chain, and in extended lifespan | 27420916 |
| 2016-06-28 10:16:00 | These findings explain how DLK specifically mediates nerve injury responses and reveal a novel cellular mechanism that ensures the specificity of neuronal kinase signaling. | 26719418 |
| 2015-04-25 10:25:00 | Independent of myosin light chain activation, RHGF-1 acts via Rho-dependent kinase LET-502/ROCK and activates a conserved, retrograde DLK-1 MAPK pathway, triggering synaptic branch retraction and overgrowth of the PLM neurite in a dose-dependent manner. | 25359212 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DLK1_CAEEL,
D6VPA3_CAEEL
UniprotKB:
O01700,
D6VPA3
UniParc:
UPI0001D8E830,
UPI000021CE84,
UPI000007738D,
UPI000021CE68,
UPI000021CE69
EMBL:
AL022593,
BX284601
EnsemblGenome:
WBGene00001008
KO:
cel:CELE_F33E2.2
|
| Nucleutide sequences |
EMBL-CDS:
CAE54891.1,
CAB06544.3,
CAE54890.1,
CAQ76474.1,
CBM41196.1
Gene_ORFName:
F33E2.2,
CELE_F33E2.2,
F33E2.2
EnsemblGenome_TRS:
F33E2.2c.1,
F33E2.2b.1,
F33E2.2a.1,
F33E2.2d.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F33E2.2d.1,
F33E2.2a.1,
F33E2.2b.1,
F33E2.2c.1
RefSeq:
NP_001129769.1,
NP_001021443.1,
NP_001251937.1,
NP_001021444.1,
NP_001021445.1
|
| Others |
UniRef100:
UniRef100_O01700
UniRef90:
UniRef90_O01700
UniRef50:
UniRef50_O01700
UniGene:
Cel.24063
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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