| Type | Description |
|---|---|
| Definition | septin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:31:00 | SEPT1 function depends on the Golgi matrix protein GOLGA2 and on centrosomal proteins, including CEP170 and components of gamma-tubulin ring complex, to facilitate the perinuclear concentration of Golgi membranes. | 30709970 |
| 2014-12-20 11:58:00 | The SEPT1 may participate in cell-cell and/or cell-substrate interaction in DJM-1 and exert its function in a coordinated manner with other septins. | 23087102 |
| 2010-01-21 00:00:00 | An increase in Sept1 expression in all oral squamous-cell carcinoma-derived cell lines compared to human normal oral keratinocytes and oral premalignant lesions suggest that Sept1 expression could contribute to cancer progression, proliferation, or both. | 17912427 |
| 2010-01-21 00:00:00 | Aurora-B binds and phosphorylates Septin1. | 16179162 |
| Type | IDs |
|---|---|
| Synonymous | DIFF6, LARP, PNUTL3, SEP1 |
| Gene |
UniProtKB-ID:
SEPT1_HUMAN,
J3KNL2_HUMAN
UniprotKB:
Q8WYJ6,
J3KNL2
UniParc:
UPI000066D948,
UPI00017A7F31,
UPI0000135858
EMBL:
AK301045,
AC127457,
AL833004,
AC116348,
AY034176,
AF308288,
BC012161,
AF085235
Ensembl:
ENSG00000180096
KO:
hsa:1731
|
| Nucleutide sequences |
EMBL-CDS:
AAG48256.1,
AAH12161.1,
AAK61491.1,
CAH56484.1,
AAL40393.1,
BAG62658.1
Ensembl_TRS:
ENST00000652617,
ENST00000321367
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498586,
ENSP00000324511
RefSeq:
XP_016878480.1,
NP_001352906.1,
NP_443070.6
|
| Others |
UniRef100:
UniRef100_Q8WYJ6
UniRef90:
UniRef90_Q8WYJ6
UniRef50:
UniRef50_Q8WYJ6
UniGene:
Hs.632176
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31515488 |
Nat Commun Robert Fragoza , Jishnu Das , Shayne D Wierbowski , Jin Liang , Tina N Tran , Siqi Liang , Juan F Beltran , Christen A Rivera-Erick , Kaixiong Ye , Ting-Yi Wang , Li Yao , Matthew Mort , Peter D Stenson , David N Cooper , Xiaomu Wei , Alon Keinan , John C Schimenti , Andrew G Clark , Haiyuan Yu |
2019-09-12 | - |
| 30709970 |
A SEPT1-based scaffold is required for Golgi integrity and function. J. Cell. Sci. Kyungyeun Song , Claudia Gras , Gabrielle Capin , Niclas Gimber , Martin Lehmann , Saif Mohd , Dmytro Puchkov , Maria Rödiger , Ilka Wilhelmi , Oliver Daumke , Jan Schmoranzer , Annette Schürmann , Michael Krauss |
2019-02-01 | - |
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26972000 |
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways. Cell Rep Javier Rodriguez , Ruth Pilkington , Amaya Garcia Munoz , Lan K Nguyen , Nora Rauch , Susan Kennedy , Naser Monsefi , Ana Herrero , Cormac T Taylor , Alex von Kriegsheim |
2016-03-22 | - |
| 26871637 |
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell Xinping Yang , Jasmin Coulombe-Huntington , Shuli Kang , Gloria M Sheynkman , Tong Hao , Aaron Richardson , Song Sun , Fan Yang , Yun A Shen , Ryan R Murray , Kerstin Spirohn , Bridget E Begg , Miquel Duran-Frigola , Andrew MacWilliams , Samuel J Pevzner , Quan Zhong , Shelly A Trigg , Stanley Tam , Lila Ghamsari , Nidhi Sahni , Song Yi , Maria D Rodriguez , Dawit Balcha , Guihong Tan , Michael Costanzo , Brenda Andrews , Charles Boone , Xianghong J Zhou , Kourosh Salehi-Ashtiani , Benoit Charloteaux , Alyce A Chen , Michael A Calderwood , Patrick Aloy , Frederick P Roth , David E Hill , Lilia M Iakoucheva , Yu Xia , Marc Vidal |
2016-02-11 |
USH1C,
PQBP1,
OPTN,
RBM5,
CDK5,
CDK7,
RABEPK,
SRRM1,
NOD1,
CD2BP2,
RBM14,
HAX1,
SLC30A9,
STK25,
SEMA4F,
SLC19A2,
CETP,
SRSF10,
SEPT9,
ALDH1L1,
RCC1,
LDB3,
AKAP10,
SEC63,
PHF21B,
HELQ,
CKB,
ERCC8,
CLCN2,
ZFYVE27,
CLPTM1,
TTC8,
C15orf40,
COL1A2,
BBS5,
ACMSD,
DNAJC19,
CPA2,
C7orf34,
CRH,
CRK,
RDH12,
MIPOL1,
ZNF688,
SLC25A10,
NKX2-5,
CTNS,
CTSD,
UPP2,
CYBB,
CYP11A1,
TSTD2,
DAO,
REM2,
DYX1C1,
DCN,
DDC,
GLIS3,
DGUOK,
DHCR7,
DMD,
E2F6,
TYMP,
EGR2,
FLCN,
EPHX1,
EYA4,
ETFA,
ETV6,
FANCC,
FANCG,
EFEMP1,
MICU2,
ZUFSP,
FCGR3A,
ABCB7,
FGA,
FGFR1,
FH,
DOLK,
KIAA0907,
ARHGEF15,
SETX,
ARHGAP26,
SPG20,
FMO3,
ETHE1,
SLC39A14,
CDK20,
SMUG1,
FXN,
FTSJ1,
MCM9,
GABRA2,
GAD1,
SUMF2,
GALT,
UNC50,
FBXO8
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24722188 |
Nat Commun Roser Corominas , Xinping Yang , Guan Ning Lin , Shuli Kang , Yun Shen , Lila Ghamsari , Martin Broly , Maria Rodriguez , Stanley Tam , Shelly A Trigg , Changyu Fan , Song Yi , Murat Tasan , Irma Lemmens , Xingyan Kuang , Nan Zhao , Dheeraj Malhotra , Jacob J Michaelson , Vladimir Vacic , Michael A Calderwood , Frederick P Roth , Jan Tavernier , Steve Horvath , Kourosh Salehi-Ashtiani , Dmitry Korkin , Jonathan Sebat , David E Hill , Tong Hao , Marc Vidal , Lilia M Iakoucheva |
2014-01-01 |
ADA,
CDH9,
CDH10,
TRIM10,
SORBS3,
PSME3,
CALCOCO2,
SPRY2,
EFS,
IKZF1,
CDR2,
NDC80,
TACC3,
CDX4,
ZBTB18,
NEBL,
SPAG5,
RBCK1,
RAI2,
VAMP5,
CPLX1,
RCBTB2,
RBPMS,
MID2,
RAPGEF4,
KLF12,
EXOSC8,
DTX2,
GALNT13,
GPRASP2,
CMTM5,
AGAP1,
RAB3IP,
SSX2IP,
PIH1D2,
RHEBL1,
PRR20A,
FSD2,
ADORA2A,
FUNDC1,
PTCHD1,
CRMP1,
CRX,
NOL4L,
DYDC1,
MIPOL1,
MGAT5B,
CTBP1,
CTBP2,
TTC23L,
ADRB2,
AMOT,
ADSL,
SAXO1,
CCDC67,
DAB1,
DAO,
OTUD7A,
MARCH10,
AP2B1,
AES,
TXLNB,
FAM9B,
DHCR7,
DHPS,
SEPT1,
DLG2,
DLX1,
DLX2,
DMPK,
DPYD,
DPYSL2,
DRD3,
ABAT,
EDA,
EIF4E,
EIF4EBP1,
EIF4EBP2,
TXLNA,
ERBB2,
ESR2,
SPERT,
REEP3,
EEF1AKMT1,
RFX6,
FGFR3,
FHIT,
IKZF3,
IKZF2,
NTNG1,
ZBTB1,
FAN1,
RPIA,
SWAP70,
SEPT6,
CEP68,
CYFIP1,
GSE1,
FAM168A
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员